大同大學 教職員資料 (Information of TTU Faculty & Staff)
　
基本資料 (Basic Info)
姓名：林銘澤 (Lin, Ming-Tse) 副教授
單位：化學工程與生物科技學系  
電話：02-21822928#6329  
手機：0917018329  
email：mtlin@gm.ttu.edu.tw  
網址：  
　
學歷 (Education)
台灣大學 農業化學所 生物化學組 碩士 (1990/9 ~ 1992/6)
　
經歷 (Experience)
大同大學 化工生技系 副主任 (2019/8 ~ 今)
大同大學 化工生技系 副教授 (2019/8 ~ 今)
大同大學 生物工程系 副教授 (1999/8 ~ 2019/7)
大同大學 生物工程系 講師 (1992/7 ~ 1999/7)
　
專長 (Specialty)
生物技術 biotechnology
遺傳工程 genetic engineering
奈米醫學 nanomedicine
　
開授課程 (Course)
生化工程 Biochemical engineering
生物化學 Biochemistry
生物統計 Biostatistics
分子生物 Molecular Biology
　
獎勵 (Award)
國際化妝品科技研討會論文獎第二名 (靜宜大學 2009-10-22)
2007年第十屆工程科技與中西醫藥應用研討會壁報論文佳作獎 (國立中興大學 2007-05-27)
　
服務 (Service)
校圖書委員 (2018-08-01 ~ 今)
系課程委員 (2008-03-01 ~ 今)
生物安全委員會 (2008-03-01 ~ 今)
台灣乳酸菌協會秘書長 (2012-02-01 ~ 2014-02-28)
校務代表 (2009-08-01 ~ 2010-07-31)
院課程委員 (2009-08-01 ~ 2017-04-30)
健康樹股份有限公司中小企業科技關懷顧問 (2009-04-01 ~ 2009-10-31)
實驗動物管理委員 (2009-01-01 ~ 2016-04-30)
系教評委員 (2008-03-01 ~ 2010-07-31)
院務委員 (2007-09-01 ~ 2009-07-31)
系課程委員 (2004-08-01 ~ 2005-07-31)
　
研究計畫 (Project)
可持續殺滅多種致病微生物之新型生物用藥開發
大同大學 B107-S01-024 執行期間：2018-01-01 ~ 2018-11-30
角蛋白生物相容性檢測
凱利得科技股份有限公司 E10701-S07-037 執行期間：2018-01-01 ~ 2018-12-31
以二階段醱酵法生產菌紅素與其抗癌應用之研究
大同大學 B106-S02-025 執行期間：2017-01-01 ~ 2017-11-30
用於腫瘤熱療法的溫度敏感性奈米水膠之製備
大同大學 B105-S03-010 執行期間：2016-01-01 ~ 2016-12-31
環狀糊精/聚異丙基丙醯胺/幾丁聚糖之微膠的製備及應用
國科會 NSC 100-2221-E-036 -010 - 執行期間：2011-08-01 ~ 2012-07-31
提升類胡蘿蔔素安定性與生物利用性之研究
大同大學 B99-S03-029 執行期間：2010-09-01 ~ 2011-07-15
感溫性奈米粒子於生物醫學的應用
補助大學跨學門科學人才培育銜接計劃 99-B4-2 執行期間：2010-01-01 ~ 2010-12-31
嗜鹽菌類胡蘿蔔素之生產及其應用 III
國科會 NSC 98-2221-E-036 -020- 執行期間：2009-08-01 ~ 2010-07-31
奈米金粒子表面修飾應用於生物感測元件
大同大學 B97-S02-015 執行期間：2008-09-01 ~ 2009-07-15
嗜鹽菌類胡蘿蔔素之生產及其應用 II
國科會 NSC 97-2221-E-036-029 執行期間：2008-08-01 ~ 2009-07-31
嗜鹽菌類胡蘿蔔素之生產及其應用
國科會 NSC 96-2221-E-036-021 執行期間：2007-08-01 ~ 2008-07-31
嗜鹽菌Haloferax mediterranei 紅色色素生產及其應用之研究
大同大學 B95-S04-066 執行期間：2006-09-01 ~ 2007-07-15
應用PCR-ELISA定量含氮廢水中之脫硝菌
大同大學 B94-S11-072 執行期間：2005-09-01 ~ 2006-07-15
結合多重PCR及雜交法檢測食品中大腸桿菌O157:H7
大同大學 B93-S10-064 執行期間：2004-09-01 ~ 2005-07-15
應用PCR與雜交法以檢測含氮廢水中之硝化與脫硝菌
國科會 執行期間：2004-08-01 ~ 2005-07-31
結合多重PCR及QCM檢測食品中出血性大腸桿菌O157:H7
大同大學 B9208-S11-079 執行期間：2003-09-01 ~ 2004-07-15
應用PCR與雜交法以檢測含氮廢水中之硝化與脫硝菌
國科會 執行期間：2003-08-01 ~ 2004-07-31
利用石英晶體微天秤檢測出血性大腸桿菌之研究
大同大學 B91-S09-057 執行期間：2002-09-01 ~ 2003-07-15
以DNA聚合酵素連鎖反應法快速檢測含氮廢水中之硝化及脫氮細菌(Ⅱ)
國科會 執行期間：2002-08-01 ~ 2003-07-31
先進生物感測系統之研發-病源菌核酸檢測系統之建立
國科會 執行期間：2002-08-01 ~ 2003-07-31
嗜鹽菌Haloferax mediterranei之polyhydroxyalkanoate (PHA) synthase和depolymerase基因選殖及性質之研究
大同大學 B90-1900-04 執行期間：2001-09-01 ~ 2002-07-15
以DNA聚合酵素連鎖反應法快速檢測含氮廢水中之硝化及脫氮細菌
國科會 執行期間：2001-08-01 ~ 2002-07-31
　
期刊論文 Refereed Paper
1. Jiann‑Shing Wu, Jan‑YI Chang, C. Will Chen, Mng-Tse Lin, Dey‑Chyi Sheu, and Shun‑Mei Lee, "Neokestose suppresses the growth of human melanoma A2058 cells via inhibition of the nuclear factor‑κB signaling pathway.," Molecular Medicine Reports, 16: 295-300, 2017 SCI 
2. Lei Zhang, Paul Chan, Zhong Min Liu, Yi Li Tseng, C. Will Chen, Ming Tse Lin, Wing P. Chan, and Ting-Kai Leung, "A technology developed from concept of acupuncture and meridiansystem, the clinical effect of BIOCERAMIC resonance on psychological related sleep disturbance with findings on questionnaire, EEG and fMRI.," Journal of Traditional and Complementary Medicine, pp. 1-7, 2017 SCI 
3. I-Yun Cheng, Shu-Chuan Liao, Ko-Shao Chen, Mu-Rong Yang, Ming-Tse Lin, and Yao-Chung Liu, "UV-induced grafting polymerization of NIPAAm hydrogel and deposit of hydroxyapatites-like films on polymer surface by atmospheric plasma treatment," Proceedings of the IEEE International Conference on Advanced Materials for Science and Engineering, pp. 416-418 EI 
4.何宜倩、林銘澤、黃秉炘、鄭仕一, "溫泉水水質檢測之研究--以耕莘專校宜蘭校區溫泉水為例," 耕莘學報, pp. 53-59, 2015
5.何宜倩、李淑芬、劉耀中、廖世傑、林銘澤, "溫泉水抗氧化及抗致突變之研究--以耕莘專校宜蘭校區溫泉水為例," 耕莘學報, 13-19, 2015
6. C. Will Chen, Shu-hui Hsu, Ming-Tse Lin, and Yi-hui Hsu, "Mass production of C50 carotenoids by Haloferax mediterranei in using extruded rice.," Bioprocess Biosyst Eng., Vol. 38, pp.2361–2367 SCI 
7. Ting-Kai Leung, Ming-Tse Lin, Chang-An Chen, Chau-Yun Hsu, Shoei-Loong Lin, and C. Will Chen, "The analysis of normalized effects on meridian current level after the photoluminescent bioceramic treatment on acupuncture points.," Journal of Alternative and Complementary Medicine, pp. 472-479, Aug. 2015 SCI 
8. K S Chen, T S Hung, H M Wu, J Y Wu, M T Lin, and C K Feng, "Preparation of thermosensitive gold nanoparticles by plasma pretreatment and UV grafted polymerization," Thin Solid Films, Vol 518, No. 24, pp. 7557-7562 SCI 
9. Chou-Chiang Kuo, Ching-An Lin, Jing-Yi Chen, Ming-Tse Lin, and Kow-Jen Duan*, "Production of cyclodextrin glucanotransferase from an alkalophilic Bacillus sp. by pH-stat fed-batch fermentation," Biotechnol Lett, Vol. 31, pp. 1723-1727; DOI 10.1007/s10529-009-0071-9 SCI 
10. Y.C. Ho, C.H. Liu, C. N. Chen, K. J. Duan, and M. T. Lin*, "Inhibitory effects of xanthohumol from hops (Humulus lupulus L.) on human hepatocellular carcinoma cell lines," Phytotherapy Research, Vol.22, pp. 1465-1468, Sep. 2008 SCI 
11. Yi-chien Ho, Ming-Tse Lin*, Kow-Jen Duan, and Yen-Shang Chen, "The Hepatoprotective Activity Against Ethanol-Induced Cytotoxicity by Aqueous Extract of Antrodia cinnamomea," J Chin Inst Chem Eng, Vol. 39, No. 5, pp. 441-447, Sep. 2008 SCI 
12. Chao-Heng Chien*, Hui-Min Yu, and Ming-Tse Lin, "The rapid temperature transfer apparatus for E. coli K12 DNA segment amplification.," Chemical Engineering Journal, Vol. 141, pp.327-331, Jul 2008 SCI 
13. Kuen-Shan Jaw, Kow-Jen Duan, and Ming-Tse Lin, "Purification of Trypsin Inhibitor from SweetPotato by Applying Immobilized Trypsin on Glutaraldehyde Activated Chitosan Beads," J. Chin Inst Chem Engrs, Vol.37, No. 2, pp. 125-129 SCI 
14.Lin, Miao-Wen, M.T. Lin , and C.T. Lin, "Copper/zinc-superoxide dismutase from lemon fruit cDNA and enzyme stability," J. Agri. Food Chem, Vol. 50, pp.7264-7270 SCI 
15.Duan, K.J., M.T. Lin, Y.C. Hung, C.T. Lin, C.W. Chen, and D.C. Sheu, "Production of GST-SOD fusion protein by recombinant E. coli XL1 Blue," J Chem Tech Biotech, Vol. 75, pp.722-728 SCI 
16.Lin, M.T., T.J. Kuo, C.T. Lin, " Molecular cloning of a cDNA encoding copper/zinc superoxide dismutase from papaya fruit and overexpression in Escherichia coli.," J. Agri. Food Chem, Vol. 46, pp.344-348 SCI 
　
短篇期刊論文 Short Paper
1.Lin, M.T., M.T. Fu, C.F. Ken, and C.T. Lin, 2000, "Cloning and characterization of a cDNA encoding for Cu/Zn-superoxide dismutase from pineapple," Plant Physiology, Vol. 123, PGR 00-021 SCI 
2.Lin, M.T., K.Y. Fu, M.T. Lin, S.F. Yang and J.F. Shaw,, "Cloning and characterization of a cDNA coding for 1-aminocyclopropane-1-carboxylae synthase from papaya fruit," Plant Physiology, Vol. 116, pp.1193 SCI 
　
國際研討會論文 International Conference Paper
1. Ming-Tse LIN, Chun-Hung TSAI, Chien-Chung CHEN, and C. Will CHEN, "Highly Aligned and Single-Layered Hollow Fibrous Membranes of Polyhydroxyalkanoates from Haloferax mediterranei ," The 6th International Conference on Bio-based Polymers, ICBP 2017, PD-161
2.Ho, YC, NC Huang, HY Kuo, CY Wang, IJ Liu, MC Yu and MT Lin, "Evaluation of general essential (ostrich) oil, survey of its transdermal properties and the skin water content," International Cosmetic-Tech Conference, pp184
3.Liu, YC, YJ Chen and MT Lin, "Enhance the production of carotenoids from a halophilic Haloferax spp. by," The Synposium of Young Asian Biochemical Engineers' Community, pp18 (A-35)
4.Ho, YC, ST Chang and MT Lin, "Antioxidative properties of a carotenoid from Haloferax spp.," The Synposium of Young Asian Biochemical Engineers' Community, pp18 (A-36)
5.Chang, HE and MT Lin, "Rapid and sensitive quantification of fentanyl in human plasma by a simple solvent extraction and liquid chromatography-tandem mass spectrometry," The Synposium of Young Asian Biochemical Engineers' Community, pp18 (A-37)
6.Ho, YC, KY Chen, CY Wang, YK Lin, MC Yu and MT Lin, "Purification of type I and type II collagen from sternal cartilage of the chick," International Cosmetic-Tech Conference and Exhibition, pp. 258
7.Ho, YC, MT Lin and CY Wang, "The pigmentation of red pigment by Haloferax mediterranei on the cultured melanocytes and phenotype-based evalution of zebrafish," International Cosmetic-Tech Conference and Exhibition, pp. 264
8.Ho, YC, IA Wang, WW Wu and MT Lin, "The inhibitory effects of red pigment from Haloferax mediterranei on the pigmentation of cultured melanocytes and phenotype-based evaluation of Zebrafish," International symposium of natural nutricosmetics, 2009ISSN-B-3
9. YC Ho, MT Lin, YS Chen, and LT Ting, "The aqueous extracted polysaccharides containing galactose from Antrodia cinnamomea prevent the hepatocyte from ethanol-induced cytotoxicity," Asia Pacific Biochemical Engineering Conference, PII-11, Nov. 2007
10. YC Ho, MT Lin, and CW Chen, "Inhibitory effects of Red Pigments Extracted from Haloferax mediterranei on Human Hepatoma Cells," Asia Pacific Biochemical Engineering Conference, PII-24, Nov. 2007
11.Lin, M.T., Y.C. Hsueh, "The effect of temperatures on denitrification and populations of denitrifying bacteria in synthetic wastewater," 12th Synposium of Young Asian Biochemical Engineers' Community, PA-25
12.Ho, Y.C., M.T. Lin, C. W. Chen, "The effect of red pigment from Haloferax mediterranei on the growth and pigmentation of cultured melanocytes," The 12th Synposium of Young Asian Biochemical Engineers' Community, PA-26
13.Tsong-Rong Yan, Ming-Tse Lin, Shiao-Ming Chang, Ching-Lung Lei, Jiann-yung Huang, Chin-Nam Lin, and, "Isolation and Identification of a Denitrifying Bacterium from Wastewater of Dextrinated Lead Azide Producing Process," Asia Pacific Biochemical Engineering Conference 2005, P2-090(MIC)
14.Lin, M.T., K.J. Duan, C.T. Lin, "The rapidly detection of nitrifying and denitrifying bacteria in wastewater by polymerase chain reaction," The 8th Symposium of Young Asian Biochemical, 1055-1059
　
區域研討會論文 Domestic Conference Paper
1.林銘澤、劉耀中, "有機酸對嗜鹽菌Haloferax生產C50類胡蘿蔔素之影響," 台灣化學工程學會58週年年會, A076
2.林銘澤、劉耀中, "提升嗜鹽菌Haloferax C50類胡蘿蔔素生產之探討," 台灣化學工程學會58週年年會, A077
3. Y C Ho, P S Wu, S T Chang, C Li, and M T Lin, "Evaluation for red pigment from halophilic Haloferax mediterranei on the antioxidative activities and pigmentation of cultured melanocytes," The 15th Conference on Biochemical Engineering, P3-12, p74
4.林銘澤、陳禹帆、黃婷沅、張雅涵、陳燕貞, "不同碳源對嗜鹽菌Haloferax mediterranei類胡蘿蔔素生產之影響," 2009台灣化學工程學會56週年年會, A074, pp.32
5.林銘澤、劉耀中、陳燕貞, "利用二階段批次饋料醱酵法提升嗜鹽菌Haloferax mediterranei類胡蘿蔔素之生產," 2009台灣化學工程學會56週年年會, A075, pp.32
6. YC Ho, JJ Chen, SC Ho, and MT Lin, "Antioxidant Activity of Paeonol, a Neuroprotective Compound Against H2O2-Induced Cytotoxicity on HTB-11 Neuroblastoma Cell Line," The 24th Joint Annual Conference of Biomedical Science, pp. 262
7.林銘澤、張舒婷、陳志成、蘇南維, "嗜鹽菌Haloferax mediterranei的類胡蘿蔔素之抗氧化活性評估," 中國農業化學學會第四十六次大會, A43, pp65
8.林銘澤、張舒婷、陳志成、蘇南維, "嗜鹽菌Haloferax mediterranei的類胡蘿蔔素對人類肝癌細胞株之細胞毒性," 中國農業化學學會第四十六次大會, A44, pp.66
9.蘇南維、方俊仁、李敏雄、林銘澤, "以Heloferax spp. 生產bacterioruberin相關類胡蘿蔔素之最適培養條件," 中國農業化學學會第四十六次大會, C12, pp. 109
10.林銘澤、蘇南維、張雅琪, "嗜鹽菌類胡蘿蔔素之快速萃取及純化," 第十三屆生化工程研討會, PI-17, pp.89
11.張雅琪、林銘澤, "以實驗設計法探討嗜鹽菌Haloferax mediterranei的類胡蘿蔔素之最適化生產," 第十三屆生化工程研討會, PI-34, pp. 106
12.張雅琪、蔡怡韋、林銘澤、陳志成, "利用降低鹽濃度以提高嗜鹽菌Haloferax mediterranei的類胡蘿蔔素之生產," 第十三屆生化工程研討會, PI-42, pp. 114
13.劉凱銘、許垤綦、王鐘毅、林銘澤、陳志成, "細胞迴流培養Haloferax mediterrani生產polyhydroxyalknoate," 第十三屆生化工程研討會, PI-65, pp. 137
14. Yi-Chien Ho, Chi-Hsien Liu, Chien-Nan Chen, Kow-Jen Duan, and Ming-Tse Lin, "Inhibitory effects of xanthohumol from hops in human hepatocellular carcinoma cell lines," The 12th conference on Biochemical Engineering, O-II-2, p16
15.陳克紹、林銘澤、洪翠禪、廖淑娟、潘杰, "奈米金的冷電漿處理及表面固定感溫性高分子," 2007年第十屆工程科技與中西醫藥應用研討會, p146-147
16.何宜倩、劉繼賢、陳建男、段國仁、林銘澤, "Xanthohumol from hops induced apoptosis in human hepatocellular carcinoma cell lines," The 22th Joint Annual Conference of Biomedical Science, P
17.薛伃君、林銘澤, "建立與應用定量競爭型聚合酶連鎖反應以定量脫硝廢水汙泥中之脫硝菌," 中國農業化學學會第四十四次大會, pp82
18. 薛伃君 and 林銘澤, "模擬脫硝廢水處理及其活性污泥中脫硝菌之定量," The 11th Biochemical Engineering Conference, Taiwan, P7-028
19. 林銘澤 and 吳捷華, "利用competitive PCR-ELISA定量nirS型脫硝菌," The 11th Biochemical Engineering Conference, Taiwan, P7-022
20. Yi-Chien Ho 何宜倩, Ming-Tse Lin 林銘澤, and C. Will Chen 陳志成, "Cytotoxic and Apoptotic Effects in Human Liver Cancer Cell Line by Red Pigment from Haloferax mediterranei," The 11th Biochemical Engineering Conference, Taiwan, P8-031
21. Tsai-Jung Lin (林彩榕) and Ming-Tse Lin (林銘澤), "Development and Application of an Indirect Competitive Enzyme-Linked Immunosorbent Assay for the Determination of Ochratoxin A," The 12th Symposium on Chemical Sensing Technology, pp33-36
22. Yi-Chien Ho, Yen-Shang Chen, and Ming-Tse Lin*, "The Aqueous Extract of Antrodia Cinnamomea Prevents the Hepatocyte from Ethanol-Induced Cytotoxicity and Induces Apoptosis of Hepatoma cells," The 21th Joint Annual Conference of Biomedical Science, P450
23. 何宜倩, 何錦玟, 林銘澤*, and 陳守堅, "The Hepatoprotective Effect of Antrodia Fermented Filtrates from Different Media Against Cytotoxicity of Hydrogen Peroxide on HepG2 Cells," Proceedings of the 2005 ClChE Annual Meeting and Conference, pp.92 (PB-61)
24. 何宜倩, 何錦玟, and 林銘澤*, "Study on the Polysaccharide Production and Anti-oxidative Capacities of Fermented Filtrates from Antrodia Grown under Different Media," Proceedings of the 2005 ClChE Annual Meeting and Conference, pp.93 (PB-65)
25.林銘澤*、吳捷華, "利用PCR-ELISA 法定量含nirS 型基因之脫硝菌," Proceedings of the 2005 ClChE Annual Meeting and Conference, pp. 94 (PB-68)
26.何宜倩、陳炎祥、林銘澤*, "Protection of ethanol and hydrogen peroxide-induced cytotoxicity by aqueous extract of Antrodia cinnamomea in HepG2 cells," 中國農業化學學會第四十三次大會, A15
27.林銘澤*、林惠敏、陳志成, "Haloferax mediterranei 之PHA synthaes 和PHA depolymerase表現之研究," Proceedings of the tenth Conference on Biochemical Engineering, 1-P-076, p51
28.林銘澤*、薛伃君, "利用即時定量PCR 快速定量脫硝廢水污泥中之脫硝菌," Proceedings of the tenth Conference on Biochemical Engineering, 1-P-084, p55
29.陳志成* 謝秋蕙 林銘澤 謝建元, "嗜鹽菌於批次饋料醱酵生產硫酸基多醣之研究," Proceedings of the tenth Conference on Biochemical Engineering, 1-P-020, p23
30. Yi-Chien Ho, Shih-Ching Ho, and Ming-Tse Lin*, "Paeonol Protects from H2O2-Induced Cytoxicity in HTB-11 Neoroblastoma Cell Line," The 20th Joint Annual Conference of Biomedical Science (2005), P431, Mar. 2005
31.皮先智，洪仲昱，郭洲獎，林銘澤，段國仁, "遺傳工程 E. coli BL21 在不同培養條件下代謝能量流之變化," Proceedings of the nineth Conference on Biochemical Engineering, 9
32.陳克紹, 陳素貞, 盧香吟, 詹婉禎, 顏聰榮, 曾菁菁, 周宏澤, 林銘澤, 吳明蓉, "應用電漿聚合膜在QCM感測元件表面固定食物病源菌DNA及檢測研究," The 10th Symposium on Sensing Technology, ppC5-C8
33.林銘澤 、林冠妤、段國仁, "以DNA聚合酶連鎖反應法快速檢測含氮廢水中之硝化及脫硝細菌," Proceedings of the 2003 ClChE Annual Meeting and Conference, pp.52
34.段國仁、林銘澤、朱朝麟、洪啟芳、洪仲昱, "遺傳工程E. coli BL21在不同培養條件下代謝能量流之變化," Proceedings of the 2003 ClChE Annual Meeting and Conference, pp.52
35.林銘澤、林冠妤、黃惠貞、段國仁, "利用競爭型聚合酶連鎖反應法進行脫硝菌之檢測與定量," Proceedings of the 8th Conference on Biochemical Engineering, 1-PO-117, pp.105
36.陳克紹、詹婉禎、陳素真、吳明蓉、林銘澤、顏聰榮, "石英壓電微天平（QCM）固定DNA探針檢測大腸桿菌O157:H7," The 9th Symposium on Sensing Technology, pp.137-140
37.林銘澤, "以DNA聚合酵素連鎖反應法快速檢測含氮廢水中之硝化及脫硝細菌," 2002 ClChE Annual Meeting and Conference, pp.10
38.林銘澤，黃惠貞，段國仁，許垤棋, "利用DNA聚合酵素連鎖反應法快速檢測脫硝菌," Proceedings of the seventh Conference on Biochemical Engineering, pp.1055-1059
39.林隆誌, 林銘澤, "以分子生物方法處理鉻酸鹽之探討," 中國農業化學學會第四十次大會, pp.107