大同大學 教職員資料 (Information of TTU Faculty & Staff)
基本資料 (Basic Info)
姓名：吳錫芩 (Wu, Hsi-Chin) 副教授
單位：機械與材料工程學系  
職務：工學院學士班（大一不分系）班主任  
電話：02-21822928 #6231  
手機：  
email：hcwu@gm.ttu.edu.tw  
網址：https://sites.google.com/site/hcwunml/home  
學歷 (Education)
National Taiwan University Institute of Biomedical Engine 博士 (2005/9 ~ 2009/6)
National Taiwan University Institute of Biomedical Engine 碩士 (2003/9 ~ 2005/6)
Tatung University Department of Materials Engine 學士 (1999/9 ~ 2003/6)
經歷 (Experience)
National Taiwan University College of Medicine Post-doc (2009/9 ~ 2010/2)
Harvard Medical School Division of Medical Sciences Visiting Fellow (2007/9 ~ 2009/2)
專長 (Specialty)
生醫材料 Biomaterials
奈米生物技術 Nanobiotechnology
組織工程 Tissue Engineering
開授課程 (Course)
探索人造世界的奇妙材料
漫談生活中的真「材」實「料」
社會設計
生物學與材料學之間的交互作用 Biomaterials: The Intersection of Biology and Materials Science
普通化學實驗(二) General Chemistry Laboratory
普通化學實驗(一) General Chemistry Laboratory
材料科學導論（一）（二） Materials Science and Engineering: Introduction
專題討論 Seminar
雜誌研讀 Seminar On Journal Readings
組織工程與再生醫學 Tissue Engineering And Regenerative Medicine
獎勵 (Award)
Honorable Mention （生醫材料組） (2013 生物醫學工程科技研討會暨國科會醫學工程學門成果發表會 2013-12-15)
102年度大專校院獎勵特殊優秀人才 (行政院國家科學委員會 2013-08-01)
優秀青年會員獎 (中華民國陶業年會 2013-05-24)
Honorable Mention-藥物制放組 (2013中華民國生醫材料及藥物制放年會暨國科會醫工學門成果發表會 2013-05-04)
Honorable Mention-生醫材料組 (2013中華民國生醫材料及藥物制放年會暨國科會醫工學門成果發表會 2013-05-04)
The 9th National Innovation Award-Excellent Award-Academic Research Category (Institute for Biotechnology and Medicine Industry 2012-11-15)
101年度大專校院獎勵特殊優秀人才 (行政院國家科學委員會 2012-09-01)
Young Investigator Award (ISOMRM) (International Symposium of Materials on Regenerati 2012-08-29)
Young Investigator Award (IEEE BMES) (World Association for Chinese Biomedical Engineers 2011-08-20)
Excellent Award (Materials Research Society Taiwan (MRS-T) 2010 Ann 2010-11-20)
Excellent Graduate Research Paper Award: Honorable Mention Award (College of Medicine, National Taiwan University 2010-04-09)
Short-Term Exchange Student Scholarship (2008-2009) (College of Engineering, National Taiwan University 2008-12-01)
Taiwan Merit Scholarship (2007-2008) (National Science Council 2008-09-10)
Excellent Graduate Research Paper Award: Excellent Award (College of Medicine, National Taiwan University 2007-04-17)
The 4th Place Award (Biomedical Engineering Creative Designs 2006-12-17)
THERMEC 2006 Outstanding Student Travel Grant (THERMEC' 2006 2006-11-17)
The Second Prize (The Fourth National Innovation Award-Student Research Contest) (Institute for Biotechnology and Medicine Industry 2006-10-17)
The Second Prize (The Third National Innovation Award-Student Research Contest) (Institute for Biotechnology and Medicine Industry 2005-10-17)
Wu Clansman Association Scholarship (2003-2009) (Wu’s Benevolence Society 2003-04-17)
Academic Award (1999-2003) (Tatung University 1999-09-01)
服務 (Service)
1. 校務會議委員 (2011-06-01 ~ 今)
2. Journal Reviewer (Biomedical Materials) (2010-05-01 ~ 今)
3. Organization Scientific Committee 2010 ISOMRM (2010-04-01 ~ 今)
4. Journal Reviewer (Biomedical Engineering-ABC) (2010-04-01 ~ 今)
5. Journal Reviewer (Materials Research Bulletin) (2010-03-01 ~ 今)
6. Organization Scientific Committee 2011陶業年會 (2010-12-01 ~ 2011-06-30)
專 利 (Patent)
1. 吳錫芩(本校教師), 林峯輝(校外教師), 王子威(校外教師), "一種具磁性的氫氧基磁性奈米顆粒及其製造方法," Taiwan Patent 096134996-I375567
2. 吳錫芩（本校教師）, 林峯輝（外校教師）, 王子威（外校教師）, "醫用超順磁奈米粒子及其製造方法," I379689
學術研究計畫(研4)
1. 陰道用奈米凝膠載體治療子宮內膜異位症之研究(II)，2024/8/1 ~ 2025/7/31
2. 載薑黃素介孔聚多巴胺奈米載體用於口服治療發炎性腸道疾病之研究，大專生研究計畫:林珍妤 ，2023/7/1 ~ 2024/2/28
3. 陰道用奈米凝膠載體治療子宮內膜異位症之研究，2022/8/1 ~ 2023/7/31
4. 奈米顆粒釋放於原位成形黏膜黏附性水膠混成複合物於陰道傳遞之研究(II)(3/3)，2021/8/1 ~ 2022/7/31
5. 鄰苯二酚接枝幾丁聚醣改質磁性氫氧基磷灰石奈米顆粒於siRNA遞送之研究，大專生計畫：周旻樺 ，2021/7/1 ~ 2022/2/28
6. 奈米顆粒釋放於原位成形黏膜黏附性水膠混成複合物於陰道傳遞之研究(II)(2/3)，2020/8/1 ~ 2021/7/31
7. 奈米顆粒釋放於原位成形黏膜黏附性水膠混成複合物於陰道傳遞之研究(II)(1/3)，2019/8/1 ~ 2020/7/31
8. 奈米顆粒釋放於原位成形黏膜黏附性水膠混成複合物於陰道傳遞之研究，2018/8/1 ~ 2019/7/31
9. 開發具標靶式共傳輸化療藥物與小干擾RNA之多功能治療性奈米載體於腫瘤治療之研究(II)，2017/8/1 ~ 2018/7/31
10. 製備具磁性、冷光介孔磷酸鈣微球於診斷治療學之應用，2017/7/1 ~ 2018/2/28
11. 開發具標靶式共傳輸化療藥物與小干擾RNA之多功能治療性奈米載體於腫瘤治療之研究，科技部 一般型研究計劃 2016/8/1 ~ 2017/11/30
12. 開發多功能生物降解型磁性奈米晶體於癌症治療之研究，國科會 一般型研究計畫 2013/8/1 ~ 2016/7/31
13. 多功能性可降解磁性奈米顆粒之開發及應用，國科會 新進人員研究計畫(個別型) 2011/8/1 ~ 2012/9/30
14. 磁性奈米顆粒基因轉殖於功能性組織工程之應用，國科會 一般型研究計畫 2011/8/1 ~ 2012/7/31
15. 中草藥鞣花對軟骨組織抗氧化發炎能力及再生修復的效果，國科會 一般型研究計畫 2010/11/1 ~ 2011/12/31
16. 功能性支架及工程化細胞於骨組織工程之應用，國科會 新進人員研究計畫 2010/8/1 ~ 2011/7/31
產學合作計畫(研9)
1. 利用3D列印製作免除傳統SLA前處理之316L骨科植材：生物相容性評估，2025/1/1 ~ 2025/11/30
2. 以探究式教學導入工程通識課程學習之研究，2024/8/1 ~ 2025/7/31
3. 具黏膜黏附性及黏膜穿透性之硫醇化Pluronic F-127奈米顆粒應用於陰道藥物遞送之研究，2024/1/1 ~ 2024/11/30
4. 導入ODIR及同儕教與學策略提升課堂學習參與意願及主動學習：以材料科學與工程導論課程為例，2023/8/1 ~ 2024/7/31
5. 原位成形之幾丁聚醣類水膠於黏膜傳遞之研究，2023/1/1 ~ 2023/12/31
6. 材料科學導論（ㄧ）：以學生為中心之教學策略，2018/8/1 ~ 2019/7/31
7. 具介孔磷酸鈣微球之製備與性質研究，2017/1/1 ~ 2017/11/30
8. 新型雙層複合材料移植替代物應用於骨軟骨再生之研究(III)，2017/1/1 ~ 2017/11/30
9. 新型雙層複合材料移植替代物應用於骨軟骨再生之研究(II)，2016/1/1 ~ 2016/11/30
10. 開發具酸鹼敏感性奈米載體應用於口服藥物傳遞，2016/1/1 ~ 2016/11/30
11. 新型雙層複合材料移植替代物應用於骨軟骨再生之研究，2015/1/1 ~ 2015/12/1
12. 製備具酸鹼敏感性聚醣複合物奈米顆粒之特性研究，2015/1/1 ~ 2015/12/1
13. 透明質酸改質磁性奈米顆粒作為癌細胞標靶治療之研究，2012/10/1 ~ 2013/12/31
14. 中草藥鞣花酸對軟骨組織再生修復的評估，2011/9/1 ~ 2012/7/15
15. 學界協助中小企業科技關懷計畫，2011/7/1 ~ 2011/12/31
16. 表皮生長因子活性分析評估，2011/1/15 ~ 2011/7/31
17. 膠原蛋白與氫氧基磷灰石奈米顆粒作為骨基質支架之評估，2010/9/1 ~ 2011/7/15
18. 學界協助中小企業科技關懷計畫，2010/7/1 ~ 2010/12/31
期刊論文 (Journal Paper)
1. Vincent K. S. Hsiao, Ming-Hao Shih, Hsi-Chin Wu, Tair-I Wu(2024). Comparative Study of Surface Modification Techniques for Enhancing Biocompatibility of Ti-6Al-4V Alloy in Dental Implants. Applied Sciences, 14, 10904. SCIE(SCI)
2. K. S. Hsiao, Yan-Cheng Lin, Hsi-Chin Wu, Tair-I Wu(2023). Surface Morphology and Human MG-63 Osteoblasic Cell Line Response of 316L Stainless Steel after Various Surface Treatments. Metals, 13(10), 1739. SCIE(SCI)
3. Hsi-Chin Wu, Wei-Ting Kuo(2021). Redox/pH-Responsive 2-in-1 Chimeric Nanoparticles for the Co-Delivery of Doxorubicin and siRNA. Polymers, 13(24), 4362. SCIE(SCI)
4. 吳錫芩（2020）。磁性氫氧基磷灰石奈米晶體於生醫上的應用。陶瓷季刊，39(2)，23-29。
5. Huang LC, Wang HC, Chen LH,, Ho C, Hsieh PH, Huang MY, Wu HC, Wang TW(2019). Bioinspired Self-assembling Peptide Hydrogel with Proteoglycan-assisted Growth Factor Delivery for Therapeutic Angiogenesis. Theranostics, 9(23), 7072–7087. SSCI
6. Wei Hong Jian, Huan Chih Wang, Chen Hsiang Kuan, Ming Hong Chen, Hsi Chin Wu, Jui Sheng Sun, Tzu Wei Wang(2018). Glycosaminoglycan-based hybrid hydrogel encapsulated with polyelectrolyte complex nanoparticles for endogenous stem cell regulation in central nervous. Biomaterials, 174, 17-30. SCIE(SCI)
7. Chang YC, Chen MH, Liao SY, Wu HC, Kuan CH, Sun JS, Wang TW(2017). Multichanneled Nerve Guidance Conduit with Spatial Gradients of Neurotrophic Factors and Oriented Nanotopography for Repairing the Peripheral Nervous System. ACS Applied Materials & Interfaces, 2017. SCIE(SCI)
8. Lee YH, Wu HC, Yeh CW, Kuan CH, Liao HT, Hsu HC, Tsai JC, Sun JS(2017). Enzyme-crosslinked gene-activated matrix for the induction of mesenchymal stem cells in osteochondral tissue regeneration. Acta Biomaterialia, 2017. SCIE(SCI)
9. Yeh CW, Wang LW, Wu HC, Hsieh YK, Wang J, Chen MH, Wang TW(2017). Development of biomimetic micro-patterned device incorporated with neurotrophic gradient and supportive Schwann cells for the applications in neural tissue engineering. Biofabrication, 2017. SCIE(SCI)
10. Lin CJ, Kuan CH, Wang LW, Wu HC, Chen YC, Chang CW, Huang RY, Wang TW(2016). Integrated self-assembling drug delivery system possessing dual responsive and active targeting for orthotopic ovarian cancer theranostics. Biomaterials, 2016. SCIE(SCI)
11. Wu HC, Wang TW, Sun JS, Lee YH, Shen MH, Tsai ZR, Chen CY, Hsu HC(2016). Development and Characterization of a Bioinspired Bone Matrix with Aligned Nanocrystalline Hydroxyapatite on Collagen Nanofibers. Materials, 2016. SCIE(SCI)
12. Wu YF, Wu HC, Kuan CH, Lin CJ, Wang LW, Chang CW, Wang TW(2016). Multi-functionalized carbon dots as theranostic nanoagent for gene delivery in lung cancer therapy. Scientific Reports, 2016. SCIE(SCI)
13. Wu HC, Hsieh SY, Wang TW, Sun JS, Kang PL(2016). Hyaluronan-immobilized Magnetic Bioceramic Nanocrystals for Active Targeting and Intracellular Hyperthermia. Journal of Biomedical Nanotechnology, 2016. SCIE(SCI)
14. Wu HC, Hsieh SY, Wang TW, Sun JS, Kang PL(2016). Targeted Delivery of Hyaluronan-Immobilized Magnetic Ceramic Nanocrystals. Journal of Biomedical Nanotechnology, 2016. SCIE(SCI)
15. Peng YS, Lai PL, Peng S, Wu HC, Yu S, Tseng TY, Wang LF, Chu IM(2014). Glial cell line-derived neurotrophic factor gene delivery via a polyethylene imine grafted chitosan carrier. Glial cell line-derived neurotrophic factor gene delivery via a polyethylene imine grafted chitosan , 2014. SCIE(SCI)
16. Lai HJ, Kuan CH, Wu HC, Tsai JC, Chen TM, Hsieh DJ, Wang TW(2014). Tailor Design Electrospun Composite Nanofibers with Staged Release of Multiple Angiogenic Growth Factors for Chronic Wound Healing. Acta Biomaterialia, 2014. SCIE(SCI)
17. 吳錫芩、沈孟翰、沈孟翰（2014）。序化之氫氧基磷灰石與膠原蛋白奈米複合材料支架之性質研究。陶業季刊，2014。
18. Yang CS, Wu HC, Sun JS, Hsiao HM, Wang TW(2013). Thermo-induced shape memory PEG-PCL copolymer as dual drug-eluting biodegradable stent. ACS Applied Materials & Interfaces, 2013. SCIE(SCI)
19. Yeh PH, Sun JS, Wu HC, Hwang LH, Wang TW(2013). Stimuli-responsive HA-PEI nanoparticles encapsulating endostatin plasmid for stem cell gene therapy. RSC Advances, 2013. SCIE(SCI)
20. Chen YY, Wu HC, Sun JS, Dong GC, Wang TW(2013). Injectable and Thermoresponsive Self-Assembled Nanocomposite Hydrogel for Long-Term Anticancer Drug Delivery. Langmuir, 2013. SCIE(SCI)
21. Goh JH, Wu HC, Chen MH, Chen MY, Chang SC, Wang TW(2013). Control of three-dimensional substrate stiffness to manipulate mesenchymal stem cell fate toward neuronal or glial lineages. Acta Biomaterialia, 2013.
22. Cheng TY, Wu HC, Huang MY, Chang WH, Lee CH, Wang TW(2013). Self-assembling functionalized nanopeptides for immediate hemostasis and accelerative liver tissue regeneration. Nanoscale, 2013.
23. Yu-Jie Huang, Hsi-Chin Wu, Nyan-Hwa Tai, Tzu-Wei Wang(2012). Carbon Nanotube Rope with Electrical Stimulation Promotes the Differentiation and Maturity of Neural Stem Cells. Small, 2012. SCIE(SCI)
24. Mateus AY, Wu HC, Lucchesi C, Ferraz MP, Monteiro FJ, Spector M(2012). Supplementation of Collagen Scaffolds with SPARC to Facilitate Mineralization. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2012. SCIE(SCI)
25. Wu HC, Wang TW, Lin FH, Sun JS(2011). Characterization of Magnetic Hydroxyapatite Nanoparticles and Potential Application for MRI Contrast Agent. Current Nanoscience, 2011. SCIE(SCI)
26. Wu HC, Wang TW, Bohn MC, Lin FH, Spector M(2010). Novel Magnetic Hydroxyapatite Nanoparticles as Non-viral Vectors for the Glial Cell-line Derived Neurotrophic Factor Gene. Advanced Functional Materials, 2010. SCIE(SCI)
27. Wu HC, Wang TW, Lin FH(2010). Evaluation of Magnetic-Hydroxyapatite Nanoparticles for Gene Delivery Carrier. Biomedical Engineering-Applications, Basis & Communications, 2010. EI
28. Hou CH, Hou SM, Hsueh YS, Lin J, Wu HC, Lin FH(2009). The in vivo Performance of Biomagnetic Hydroxyapatite Nanoparticles in Cancer Hyperthermia Therapy. Biomaterials, 2009. SCIE(SCI)
29. Wang TW, Wu HC, Wang HY, Tsuang YH, Lin FH, Lin FH(2008). Regulation of Adult Human Mesenchymal Stem Cells into Osteogenic and Chondrogenic Lineages by Different Bioreactor System. Journal of Biomedical Materials Research Part A, 2008. SCIE(SCI)
研討會論文 (Conference Paper)
1. 吳錫芩、郭威廷（2023）。Redox- and pH- responsive polymeric nanoparticles for Cancer Drug Delivery。2023 BMES Annual MeetingUnited States of America。
2. 周旻樺、吳錫芩（2022）。DOPA-chitosan modified magnetic hydroxyapatite nanoparticles for siRNA delivery。2022年幾丁質幾丁聚醣暨生物材料研討會R.O.C。
3. 周旻樺、謝沅佑、劉文凱、卓展鏵、吳錫芩、賴躍仁、林楷潔（2022）。Warminate微型癌症磁熱療機。2022青年啟動創業台灣創業競賽R.O.C。
4. 周旻樺、謝沅佑、劉文凱、卓展鏵、吳錫芩、賴躍仁（2022）。磁樂。2022全國大專校院Healthy x Happy創新創業競賽R.O.C。
5. HC Wu, SF Zhou(2022). Progesterone-loaded thermosensitive hydrogels for vaginal drug delivery. 2022 中華民國生醫材料及藥物制放學會年會暨 科技部生科司工程醫學學門成果發表會. R.O.C.
6. Hsi-Chin Wu, Jing-Yun Lin(2021). Magnetic responsive Targeted Hydroxyapatite Nanocrystal as a Potential Chemohyperthermia Mediator. 2021 Materials Research Society-Taiwan International Conference (2021 MRSTIC)-invited. R.O.C.
7. Hsi-Chin Wu, Wei-Ting Kuo(2021). Self-crosslinked hyaluronic acid conjugated calcium phosphate hybrid nanoparticle for siRNA delivery. Biomaterials International 2021. R.O.C.
8. Hsi-Chin Wu, Wei-Ting Kuo(2021). Catechol-conjugated thiolated hyaluronic acid modified calcium phosphate nanoparticels for targeted siRNA delivery. 2021中華民國生醫材料及藥物制放學會年會-invited（頁 28）. R.O.C.
9. HC Wu, HY Yu, TW Wang, JS Sun(2013). Injectable in Situ Forming pH-responsive Hydrogel as Cell/Drug Delivery Carrier. The 13th Pacific Polymer Conference (PPC2013). United States of America.
10. Chang YC, HC Wu, TW Wang, JS Sun(2013). An Injectable Thermosensitive Hydrogel Loaded with Antioxidant Ellagic Acid for Cartilage Tissue Engineering. The 4th Asian Biomaterials Congress (ABMC). United States of America.
11. HC Wu, SY Hsieh, TW Wang(2013). Novel Magnetic Hydroxyapatite Nanocrystallite for Tumor Therapy Application: Preparation, Characterization and Targeting. The 4th Asian Biomaterials Congress (2013 ABMC). United States of America.
12. TW Wang, HC Wu, Cheng TY, Chen MH(2013). Neural Stem Cells Encapsulated in Functionalized Self-assembling Peptide Hydrogel for Brain Tissue Engineering. The 4th Asian Biomaterials Congress (2013 ABMC). United States of America.
專書 (Book)
1. Shiao-Wen Tsai, Wu, Hsi-Chin(2022). Surface Coating for Biomedical Applications. MDPI/ Coatings. https://www.mdpi.com/journal/coatings/special_issues/surf_coat_biomed_appl.