大同大學 教職員資料 (Information of TTU Faculty & Staff)
基本資料 (Basic Info)
姓名：顏聰榮 (Yan, Tsong-Rong) 教授
單位：生物工程學系  
電話：02-25925252-3315-23  
手機：0912559722  
email：tryan@ttu.edu.tw  
網址：  
學歷 (Education)
日本國 東京大學 應用生命科學 博士 (1983/3 ~ 1987/9)
經歷 (Experience)
台灣乳酸菌協會   榮譽理事 (2016/03 ~ 迄今)
大同大學 生物工程學系 榮譽教授 (2018/02 ~ 今)
大同大學 生物工程學系 教授 (1998/9 ~ 2018/01)
台灣乳酸菌協會   理事長 (2011/1 ~ 2015/12)
大同大學 生物工程學系 副教授 (1988/4 ~ 1998/8)
食品工業發展研究所 食品加工組 研究員 (1987/4 ~ 1988/3)
專長 (Specialty)
生物化學 Biochemistry
酵素化學 Enzymology
機能性食品學 Functional Foods
基因工程 Genetic engineering
開授課程 (Course)
生物化學 Biochemistry
生醫檢測 Biomedical sensors
細胞培養技術 Cell culture technology
食品安全與功能 Food safety and functionality
食品衛生與安全 Food Sanitation and Safety
機能性食品學 Functional Foods
分子生物學 Molecular biology
獎勵 (Award)
台灣乳酸菌學會第五屆學術研討會壁報論文優等獎 (台灣乳酸菌協會 2011-10-29)
大學跨學門科學人材培育銜接計畫 (大同大學 2011-07-08)
第十五屆化學感測器科技研討會最佳論文獎 (台灣化學感測器科技協會 2009-05-16)
台灣乳酸菌學會第三屆學術研討會最佳壁報論文獎 (台灣乳酸菌學會 2008-12-15)
年度論文佳作獎 (大同大學 2007-11-22)
論文佳作獎 (大同大學 2006-11-13)
第八屆中西醫藥應用與工程科技研討會壁報論文比賽優秀論文獎 (中西醫藥應用與工程科技學會 2005-05-28)
服務 (Service)
1. 台灣乳酸菌協會 榮譽理事 (2016-03-01 ~ 今)
2. 新北市 中山國中 榮譽會長 (2008-10-01 ~ 今)
3. 新北市板橋市光華聯誼會會長 (2004-04-01 ~ 今)
4. 主辦「益生菌在臨床上的運用」學術與產業應用研討會 (2015-11-01 ~ 2015-11-30)
5. 主辦 「乳酸菌及益生質之多重應用」學術與產業應用研討會 (2014-11-01 ~ 2014-11-30)
6. 主辦「從研發到上市--乳酸菌開發實務研討會」 (2014-06-01 ~ 2014-06-30)
7. 主辦 益生菌國際研討會暨台灣乳酸菌協會十周年紀念大會 (2014-04-01 ~ 2014-04-30)
8. 臺彎乳酸菌協會 第六屆理事長 (2014-01-01 ~ 2016-03-31)
9. 內控執行小組成員 (2014-01-01 ~ 2017-07-31)
10. 主辦「益生菌及其代謝物之多重應用」學術與產業應用研討會 (2013-11-01 ~ 2013-11-30)
11. 主辦「功能性乳酸菌開發與技術服務聯盟」學術與產業應用研討會 (2013-06-01 ~ 2013-06-30)
12. 台北官邸管委會主委 (2013-04-01 ~ 2018-05-31)
13. 主辦 「道微生物之最新研究」研討會 (2012-11-01 ~ 2012-11-30)
14. 主辦「腸道微生物之最新研究趨勢」研討會 (2012-06-01 ~ 2012-06-30)
15. 台灣乳酸菌學會 第五屆 理事長 (2011-11-01 ~ 2014-11-30)
16. 內控執行小組 (2011-08-01 ~ 2012-07-31)
17. 教師申訴評議委員 (2011-08-01 ~ 2012-07-31)
18. 生工系 系評委員 (2010-08-01 ~ 2008-11-30)
19. 科管學會 產業座談-生物科技/ 醫療照護產業 與談人 (2009-12-01 ~ 2009-12-31)
20. 自強工業科學基金會工業為生物之應用與培養課程講師 (2009-11-01 ~ 2009-11-30)
21. 台北官邸 管委會主委 (2009-05-01 ~ 2010-04-30)
22. 2007能源與光電鍍膜科技研討會 總務組 (2008-12-01 ~ 2008-12-31)
23. 台灣乳酸菌協會 第三屆理事 (2008-11-01 ~ 2010-12-31)
24. 大同大學研發處學 尖端科技研究中心主任 (2008-08-01 ~ 2009-07-31)
25. 光電所教師評審委員會委員 (2008-03-01 ~ 2010-11-30)
26. 中山國中 志工大隊 日文教師 (2008-02-01 ~ 2008-06-30)
27. 台北縣中山國民中學 家長會會長 (2007-10-01 ~ 2008-10-31)
28. 兆鼎檢驗科技有限公司 顧問 (2007-05-01 ~ 2008-04-30)
29. 主辦2007跨國三校學術研討會 (2007-05-01 ~ 2007-05-31)
30. 光電所教師評審委員會委員 (2007-03-01 ~ 2008-02-29)
31. 大同大學研發處學術交流組主任, 尖端科技研究中心主任 (2006-10-01 ~ 2008-07-31)
32. 全國中小學家長協會學術評鑑召集人 (2006-08-01 ~ 2008-10-31)
33. 中華醫事學院 生物科技系課程發展顧問 (2006-08-01 ~ 2007-07-31)
34. 台灣乳酸菌學會 第二屆常務理事 (2005-09-01 ~ 2007-09-30)
35. 主辦乳酸菌前瞻性科技發展研討會及第三屆台灣乳酸菌學會年會 (2005-09-01 ~ 2005-09-30)
36. 中山國中家長會 副會長 (2005-09-01 ~ 2007-10-31)
37. 工學院院評委員 (2004-08-01 ~ 2006-07-31)
38. 參加BioTaiwan 2004 展出 大同生技產業研發成果展 (2004-07-21 )
39. 主辦第二屆亞洲乳酸菌國際研討會 會場展出組 (2003-11-14 )
40. 參加 BioTaiwan 2003生技大展 大同大學建教成果展 (2003-07-23 )
41. 技術學院評鑑醫藥群生技組召集人 (2002-01-01 ~ 2003-12-31)
42. 板橋國小 家長會 常務委員 (1999-09-01 ~ 2005-08-31)
43. 生物工程系主任兼所長 (1999-08-01 ~ 2004-07-31)
專 利 (Patent)
1. 陳克紹, 陳素真, 詹婉禎, 顏聰榮, 曾菁菁, "核酸生物感測裝置及其製備方法," 中華民國發明專利第 I 252919 號, Apr. 2006
2. 李昭法、顏聰榮、郭正興, "可攜式石英晶體微天平," 中華民國發明專利I250268號
3. 李昭法*, 顏聰榮, 郭正興*; *大同公司, "System for measuring resonabt frequency and delay time of quartz crystal microbalance," US patent 7,509,860 B2
4. 李昭法, 顏聰榮, 郭正興, "量測石英晶體微天平(QCM)反應頻率及延遲時間之系統," 中華民國發明專利第 I325050號
5. Chao-Fa Lee, Cheng-Hsing Kuo, and Tsong-Rong Yan, "Dual mode measurement system with quartz crystal microbalance ," US 7,814,795 B2
6. 李昭法, 顏聰榮, 郭正興, "細胞量測系統," 中華民國發明專利第I432722號
產學合作計畫(研9)
1. 大熊酵素抗氧化成份之分析，2018/1/1 ~ 2018/12/31
期刊論文 (Journal Paper)
1. Ching-Hung Chan, Li-Han Chen, Kuang-Yu Chen, I-Hung Chen, Kung-Ta Lee, Liang-Chuan Lai, Ming-Tse Lin, Tsong-Rong Yan(2024). Single-strain probiotics enhance growth, anti-pathogen immunity, and resistance to Nocardia seriolae in grey mullet (Mugil cephalus) via gut microbiota modulation.. Animal Microbiome, 6, 67. SCIE(SCI)
2. Huey Sheng Jeng,, Tsong Rong Yan, Jing Yi Chen(2020). Treating vaginitis with probiotics in non pregnant females: A systematic review and meta analysis. Experimental and Therapeutic Medicine, 20(4), 3749-3760. SCIE(SCI)
3. Teng-Ho Wang, Teng-Ho Wang, Yi-Shing Leu, Yi-Shing Leu, Nai-Yu Wang, Nai-Yu Wan, Chang-Pan Liu, Tsong-Rong Yan, Chang-Pan Liu, Tsong-Rong Yan(2018). Prevalence of different carbapenemase genes among carbapenem-resistant Acinetobacter baumannii blood isolates in Taiwan. Antimicrobial Resistance and Infection Control, 7(1), 123. SCIE(SCI)
4. Teng-Ho Wang, Teng-Ho Wang, Yi-Shing Leu, Yi-Shing Leu, Nai-Yu Wang, Nai-Yu Wan, Chang-Pan Liu, Tsong-Rong Yan, Chang-Pan Liu, Tsong-Rong Yan(2018). Prevalence of different carbapenemase genes among carbapenem-resistant Acinetobacter baumannii blood isolates in Taiwan. Antimicrobial Resistance and Infection Control, 7(1), 123. SCIE(SCI)
5. Chnag-Pan Liu, Te-Li Chen, Nai-Yu Wang, Shang-Fan Chou, Jung-Chun Lin, Tsong-Rong Yan(2017). Detection of Pseudomonas aeruginosa isolates carrying the blaOXA-142 extended-spectrum b-lactamase gene in Taiwan. Journal of Microbiology, Immunology and Infection, 50, 68-74. SCIE(SCI)
6. Chang-Pan Liu, Shou-Chuan Shih, Nai-Yu Wang, Alice Y. Wu, Fang-Ju Sun, Shan-Fan Chow, Te-Li Chen, Tsong-Rong Yan(2016). Risk factors of mortality in patients with carbapenem-resistant Acinetobacter baumannii bacteremia. Journal of Microbiology, Immunology and Infection, 49, 934-940. SCIE(SCI)
7. Chien-Huang Li, Tsong-Rong Yan(2014). Use Aspergillus niger β-glucosidase II gene (bglII) promoter elements to construct an efficient expression vector. Journal of The Taiwan Institute of Chemical Engineers, 45(3), 749-754. SCIE(SCI)
8. Shiao-Ming Chang, Tsong-Rong Yan(2014). Genetic engineering techniques for lactic acid bacteria: consstruction of a stable shuttle vector and expression vector for β-glucuronidase. Biotechnology Letters, 36(1), 327-335. SCIE(SCI)
9. Tsong-Rong Yan, Shi-Min Chen, Yung-Yue Chang, Shiao-Ming Chang(2013). Effects of probiotic lactic acid bacteria on the growth of the gut pathogenic microorganisms. 7th Asian Conference on Lactic Acid Bacteria and Academic and Cultural Visits, 2013.
10. Shiao-Ming Chang, Chi-Lin Tsai, Wan-Chen Wee, Tsong-Rong Yan(2013). Isolation and functional study of potentially probiotic Lactobacillus from Taiwan traditional paocai. African Journal of Microbiology Research, 7, 683-691. SCIE(SCI)
11. (2012). Cloning, Purification, and Characterization of a Heat- and Alkaline-Stable Endoglucanse B from Aspergillus niger BCRC 31494. Molecules, 17(8), 9774-9789. SCIE(SCI)
12. Cha-Fa Lee, Tsong-Rong Yan, Deng-Ho Wang(2012). Long-term monitoring of Caco-2 cell growth process using a QCM-cell system. Sensors and Actuators B: Chemical, 166-167, 165-171. SCIE(SCI)
13. 顏聰榮、李昭法、王登鶴（2011）。石英晶體微量天平在生物檢測之技術發展及其應用。化工，58 (4)。
14. Hung-Che Chou, Tsong-Rong Yan(2010). Applying the quartz crystal microbalance technique to detect the epithelial cell tight junction integrality of Caco-2 cells. Analytical Letters, 43(13), 2009-2018. SCIE(SCI)
15. Hung-Che Chou, Tsong-Rong Yan, Chao-Fa Lee(2009). Matters needing attention for applying the quartz crystal microbalance technique to detect the cell morphology. Biochemical Engineering: Applications, Basis and Communications, 21(6), 415-420. SCIE(SCI)
16. Chao-Fa Lee, Tsong-Rong Yan, Hung-Che Chou(2009). IMPROVE THE DATA ACQUISITION SYSTEM OF A QCM SENSOR BY INCREASING THE SAMPLING RATE OF FREQUENCY AND AMPLITUDE. Biomedical Engineering: Applications, Basis and Communications, 21(6), 405–410. SCIE(SCI)
17. (2009). Detecting cells on the surface of a silver electrode quartz crystal microbalance using plasma treatment and graft polymerization. Colloids and surfaces B: Biointerfaces, 73, 244-249. SCIE(SCI)
18. 顏聰榮（2008）。台灣乳酸菌及發酵乳製品之最新發展。化工，55(4)，69-76。
19. Hong-Yu Lin, Yu-Chia Tsao, Woo-Hu Tsai, Yi-Wen Yang, Tsong-Rong Yan, Bor-Chiou Sheu(2007). Development and application of side-polished fiber immunosensor based on surface plasmon resonance for the detection of Legionella pneumophila with ha. Sensor and Actuators A, 138, 299-305. SCIE(SCI)
20. Shou-Chien Chen, Hsiao-Ling Chang, Tsong-Rong Yan, Yan-Tzong Cheng, Kow-Tong Chen(2007). An Eight-Year Study of Epidemiologic Features of Enterovirus 71 Infection In Taiwan. Am. J. Trop. Med. Hyg.,, 77(1), 188-191. SCIE(SCI)
21. Shiao-Ming Chang 1, Tsong-Rong Yan 1(2007). DNA sequence analysis of a cryptic plasmid pL2 from Lactococcus lactis subsp. lactis. Biotechnology Letters, 29. SCIE(SCI)
22. Ko-Shao Chen, Su-Chen Chen, Hong-Ru Lin, Tsong-Rong Yan, Chin-Chin Tsen(2007). A novel technique to immobilize DNA on surface of a quartz crystal microbalance by plasma treatment and graft polymerization. Materials Science and Engineering C, 27, 716-724. SCIE(SCI)
23. Shou-Chien Chen, Shan-Tair Wang, Kow-Tang Chen, Tsong-Rong Yan, Li-Hui Tang, Chiung-Chao Lin, Su-(2006). Analysis of the influence of therapy and viral suppression on high-risk sexually transmitted infections amoung patients with human immunodeficiency vi. Clinical Microbiology and Infection, 12, 660-665. SCIE(SCI)
24. Ko-Shao Chen, Ko-Shao Chen, 1 Yuan-An Ku, 1 Hong-Ru Lin, 2 Tsong-Rong Yan, 3 Dey-Chyi Sheu(2006). Surface Grafting Polymerization of N-Vinyl-2-pyrrolidone onto a Poly(ethylene terephthalate) Nonwoven by Plasma Pretreatment and Its Antibacterial Act. Inc. J Appl Polym Sci, 10, 803– 809. SCIE(SCI)
25. Ko-Shao Chen, Yuan-An Ku, Hong-Ru Lin, Tsong-Rong Yan, Dey-Chyi Sheu, Tin-Mo Chen, Feng-Huei Lin(2005). Preparation and Characterization of pH-Sensitive Poly(N-Vinyl 2-Pyrrolidone/Itaconic Acid) Copolymer Hydrogels. Materials Chemistry and Physics, 91(2-3). SCIE(SCI)
26. 顏聰榮（2005）。益生性乳酸菌及其保健功能。生物產業，16(2)，57-69。
27. Tsong-Rong Yan, Shiao-Ming Chang, Chien-Hsein Chen(2003). Studies on high acid producing lactic acid bacteria flora and analysis of their plasmids in. Taiwanese J. of Agric. Chem. Food Sci.,, 39, 284-290.
28. 顏聰榮、顏聰榮、陳建先（2001）。市售乳酸發酵飲料中高。台灣農業化學與食品科學，39(4)，284-290。SCIE(SCI)
29. 顏聰榮、顏聰榮、陳建先（2001）。市售乳酸發酵飲料中高。台灣農業化學與食品科學，39(4)，284-290。SCIE(SCI)
30. 顏聰榮、陳建先、高炳煌（1996）。乳酸菌質體 DNA 之研究。中國農業化學會誌，34(6)，723-731。
研討會論文 (Conference Paper)
1. Tsong-Rong Yan, Shiao-ming Chang, Shi-ming Chen(2016). Ability of Lactobacilli to inhibit Clostridium difficile adhesion on Caco-2 cells. 4th International Symposium and Meeting of the Asian Federation of the Societies for Lactic Acid Bac（頁 45）. United States of America.
2. Tsong-Rong Yan(2016). Fuctional and application of Probiotics: Probiotic application to sake-lees fermentation. International conference on beneficial microbes 2014（頁 32）. United States of America.
3. 顏聰榮、蘇大智（2016）。微脂粒包覆改善低口服吸收率藥物通透率之研究。中国颗粒学会第九届学术年会暨海峡两岸颗粒技术研讨会論文集Mainland China。
4. Shiao-Ming Chang, Shi-Ming Chen, Tsong-Rong Yan(2015). Lactobacilli protect tight junction from Clostridium difficile damage in Caco-2 cells. The 8th Asian Conference on Lactic Acid Bacteria（頁 82）. United States of America.
5. Tsong-Rong Yan, Shi-Min Chen, Yung-Yue Chang, Shiao-Ming Chang(2013). Effects of probiotic lactic acid bacteria on the growth of the gut pathogenic microorganisms. 7th Asian Conference on Lactic Acid Bacteria and Academic and Cultural Visits（頁 1）. United States of America.
6. Shiao-Ming Chang, Tsong-Rong Yan(2013). Potential of two Lactobacillus strains to induce the Th1 immune response. 7th Asian Conference on Lactic Acid Bacteria and Academic and Cultural Visits（頁 2）. United States of America.
7. Chi-Yuan chan, Tsong-Rong Yan(2012). Sake-lees fermented with lactic acid bacteria inhibits adipogenesis of 3T3-L1 pre-adipocyte. The 7th International Symposium on Lactic Acid Bacteria and Health & The 3rd Asian Symposium on Lact（頁 47）. United States of America.
8. Tsong-Rong Yan, Caty Hsu(2011). Effect of Lactic Acid Bacteria-fermented sake lees on activating CYP2E1 activity and inhibiting ROS-formation in HEPG2 cell. International Union of Microbiologic Societies 2011 Congress, Sapporo, Japan. Japan.
9. Chao-Fa Lee, Tsong-Rong Yan, ung-Che Chou, Zong-Yan Lin(2010). A quartz crystal microbalance cell-culture incubation system. Proceedings of 2010 International Innovation and Invention Conference, pp. 123-128, Sep. 26-28, Taip. R.O.C.
10. Chang Shio-Ming, Yan Tsong-Rong(2010). Construction and expression of beta-glucosidase in Lactic acid bacteria expression vector. International symposium on Lactic acid bacteria（頁 74）. United States of America.
11. Chang Shiao-Ming, Du Ming-Jie, Cheng Shu-Wen, Yan Tsong-Rong(2010). Inhibition of tyrosinase activity and melanin accumulation ability by lactic acaid bacteria fermented-beer lees. International symposium on Lactic acid bacteria（頁 93）. United States of America.
12. Yan Tsong-Rong, Chang Shiao-Ming, Du Ming-Jie, Cheng Shu-Wen(2010). Studies on antioxidant activity of Vinasse lees and its fermentation broth with lLacatic acid bacteria. International symposium on Lactic acid bacateria. United States of America.
13. Yu-Chia Tsao, Yi-Wen Yang, Woo-Hu Tsai, Tsong-Rong Yan(2007). Side-polished fiber immunosensor based on surface plasmon resonance dor fetection of Legionella pneumophila. Proc. SPIE.. United States of America.
14. Jing-Ping, Wang, Tsong-Rong Yan(2007). Inhibition of tyrosinase activity and regulating melanin production. The 4th Asian Conference on Lactic Acid Bacteria, Oct. 2007, Shanghi, China（頁 96）. Mainland China.
15. Chao-Fa Lee1, Hung-Che Chou1, Shou-Chien Chen1, Ko-Shao Chen2, Tsong-Rong, Yan1(2005). Measurement of the Response of Quartz Frequency and Postponement Time for QCM Biosensor to Detect Vibrio Parahaemolyticus. YABEC symposium Proceedings,（頁 23）. United States of America.
16. Shiao-Ming Chang, Tsong-Rong Yan(2005). Construction of shuttle vector and food grade expression vector in Lactococcus lactis. 9th National Congress of Indonesian Society for Microbiology & 3rd Asian Conference for LAB, Bali, I（頁 156）. Indonesia.
17. Tsong-Rong Yan, Dan-Wan Lou(2005). Effect of survival of Lacatic acid bacteria on adhesion onto gastrointestinal cells. 9th National Congress of Indonesian Society for Microbiology & 3rd Asian Conference for LAB, Ba（頁 164）. United States of America.
18. Tsong-Rong Yan1, Cheng-Hsing Chen1, Chin-Long Yeh2(2005). Effect of Lactobacillus acidophilus GG on Adhesion of Clostridium difficile onto Caco-2 Cell Monolayer. APBioChEC05 Biochemical Engineering from GEnomics to Human Well-Being. United States of America.
19. Tsong-Rong Yan*1, Ming-Tse Lin1, Shiao-Ming Chang1, Ching-Lung Lei2, Jiann-yung Huang2, Chin-Nam Lin(2005). Isolation and characterization of a novel denitrifying bacterium from wastewater of dextrinated lead azide producing process. APBioChEC05 Biochemical Engineering from GEnomics to Human Well-Being（頁 218）. United States of America.
20. Tsong-Rong Yan, Chi-Fu Chou(2004). Cloning and regulator prediction of Aspergillus niger beta-glucosidase II. YABEC symposiu mproceeding（頁 24-28）. United States of America.
21. Tsong-Rong Yan(2004). Function and Application of Probiotics: Probiotic application to sake-lees fermentation. International conference on beneficial microbes 2014（頁 32）. United States of America.
22. 張效銘、顏聰榮（2003）。動物糞便中之乳酸菌分離鑑定及其當作益生菌之分析。第八屆生化工程研討會論文摘要集（頁 56-60）。R.O.C。
23. Chin-Long Yeh1, Chi-Hsien Wang, 2 Sheng-Hsiung Chen2, Tsong-Rong Yan2(2003). Effects of Lactobacillus acidophilus GG (L.GG) on transport of antibiotics across Caco-2 cell line monolayer. YABEC symposium Proceedings, 2003, Nov. 13-15, Korea. Republic of Korea.
24. Chin-Long Yeh1, Chi-Hsien Wang, 2 Sheng-Hsiung Chen2, Tsong-Rong Yan2(2003). Effects of Lactobacillus acidophilus GG (L.GG) on transport of antibiotics across Caco-2 cell line monolayer. YABEC symposium Proceedings,. Republic of Korea.
專書 (Book)
1. 顏聰榮（2008）。奈米生物用語辭典。全華圖書股份有限公司。(譯著)。