大同大學教師資料

大同大學教職員資料 (Information of TTU Faculty & Staff)

基本資料 (Basic Info)

姓名：李綉鈴 (Lee, Shiow-Ling) 教授

單位：生物工程學系

電話：02-25925252 ex 3315 ex 20

手機：

email：slee@ttu.edu.tw

網址：

學歷 (Education)

國立臺灣大學食品科技研究所博士 (1986/9 ~ 1991/7)

國立臺灣大學園藝系學士 (1982/9 ~ 1986/6)

經歷 (Experience)

大同大學生物工程系教授 (1999/8 ~ 今)

大同工學院生物工程系教授 (1998/8 ~ 1999/7)

大同工學院生物工程系副教授 (1991/9 ~ 1998/7)

專長 (Specialty)

生物性香料 Bioflavor

保健食品研發 Development of functional foods

食品生物技術 Food Biotechnology

食品微生物學 Food Microbiology

微生物發酵 Microbial Fermentation

開授課程 (Course)

生物學 Biology

食品生物技術 Food Biotechnology

食品發酵學 Food Fermentation

生物學實驗 Laboratory Experiments in Biology

微生物學實驗 Laboratory Experiments in Microbiology

遺傳工程技術與應用 Technique and Application in Genetic Engineering

應用微生物技術 Technique in Applied Microbiology

獎勵 (Award)

98學年度優良導師 (大同大學 2010-11-16)

96年度論文優等獎 (大同大學 2007-11-12)

95學年度基礎案成果海報優選 (大同大學 2007-09-27)

93學年度優良教師 (大同大學 2005-10-04)

服務 (Service)

1.	應用外語系系教評委員 (2012-08-01 ~ 今)
2.	院評委員 (2005-08-01 ~ 今)
3.	生物/微生物實驗室管理 (1991-09-01 ~ 今)
4.	工業設計系系評委員 (2023-08-01 ~ 2024-01-31)
5.	工業設計系系評委員 (2022-02-01 ~ 2022-07-31)
6.	私立延平高中申請大學入學模擬面試 (2019-03-01 ~ 2019-03-31)
7.	私立延平高中申請大學入學模擬面試 (2018-04-01 ~ 2018-04-30)
8.	慈濟學報期刊論文評審委員 (2018-04-01 ~ 2018-04-30)
9.	學生申訴評議委員 (2017-08-01 ~ 2018-07-31)
10.	私立延平高中申請大學入學模擬面試 (2017-03-01 ~ 2017-03-31)
11.	新北市立新店高中申請大學入學模擬面試 (2017-03-01 ~ 2017-03-31)
12.	Energy & Fuels 期刊論文評委員 (2016-11-01 ~ 2016-11-30)
13.	J. Food Drug Anal. 期刊論文評審委員 (2016-08-01 ~ 2016-08-31)
14.	學生獎懲委員會委員 (2016-08-01 ~ 2017-07-31)
15.	慈濟學報期刊評審委員 (2016-06-01 ~ 2016-06-30)
16.	私立延平高中申請大學入學模擬面試 (2015-03-01 ~ 2015-03-31)
17.	校評會委員 (2014-08-01 ~ 2023-07-31)
18.	私立延平高中申請大學入學模擬面試 (2014-03-01 ~ 2014-03-31)
19.	Biotech. Appl. Biochem. 期刊論文評審委員 (2014-03-01 ~ 2014-03-31)
20.	J. Food Drug Anal. 期刊論文評審委員 (2013-12-01 ~ 2013-12-31)
21.	J. Food Drug Anal. 期刊論文評審委員 (2013-10-01 ~ 2013-10-31)
22.	Afr. J. Microbiol. Res. 期刊論文評審委員 (2013-08-01 ~ 2013-08-31)
23.	J. Food Drug Anal. 期刊論文評審委員 (2013-07-01 ~ 2013-07-31)
24.	私立大同高中申請大學入學模擬面試 (2013-03-01 ~ 2013-03-31)
25.	私立延平高中申請大學入學模擬面試 (2013-03-01 ~ 2013-03-31)
26.	私立大同高中申請大學入學模擬面試 (2012-03-01 ~ 2012-03-31)
27.	北二區大專院校 "輔導主任經驗傳承會議" 主講人 (2011-11-01 ~ 2011-11-30)
28.	Journal of Fisheries Society of Taiwan 期刊論文審查委員 (2011-07-01 ~ 2011-07-31)
29.	系評委員 (2010-08-01 ~ 2019-07-31)
30.	化工技術化工與生物技術專輯主編 (2010-04-01 ~ 2010-07-31)
31.	品德教育推廣委員會委員 (2010-03-01 ~ 2010-07-31)
32.	學務處導師室主任 (2009-08-01 ~ 2011-07-31)
33.	經費稽核委員 (2007-08-01 ~ 2009-07-31)
34.	校評會委員 (2005-09-01 ~ 2010-07-31)
35.	研究所導師 (2002-09-01 ~ 2009-08-31)
36.	大學部導師 (1999-01-01 ~ 2001-07-31)
37.	大學部導師 (1993-09-01 )

專利 (Patent)

1.	游吉陽 (本校教師)、李綉鈴 (本校教師)、官宜靜 (本校教師)、莊喬安 (本校學生)。, "以仿生物矽化反應提升酵素活性之方法及其套組。 ," 中華民國專利證書號 1419972, 2013,12,21

學術研究計畫(研4)

1.	蔬菜生長檢測，2018/1/1 ~ 2018/11/30
2.	藥用植物含羞草預防皮膚光老化機能性之探討(第二年)，國科會一般型研究計劃 2013/8/1 ~ 2014/7/31
3.	藥用植物含羞草預防皮膚光老化機能性之探討，國科會一般型研究計劃 2012/8/1 ~ 2013/7/31
4.	仿生氧化矽粒子包覆Pseudomonas cepacia酯解酶及生質柴油相關應用，國科會一般型研究計劃 2010/8/1 ~ 2011/7/31
5.	利用紅麴菌開發具有多種保健機能性之發酵大豆食品(II)-發酵性質與抗氧化活性探討，國科會一般型研究計畫 2005/8/1 ~ 2006/7/31
6.	利用紅麴菌開發具有多種保健機能性之發酵大豆食品，國科會一般型研究計畫 2004/8/1 ~ 2005/7/31
7.	Pichia fermentans L-5乙酸酯合成酵素之基因(aat)選殖與表現 (II) -- aat 之大量表現，國科會一般型研究計畫 2003/8/1 ~ 2004/7/31
8.	Pichia fermentans L-5 乙酸酯合成酵素之基因選殖與表現，國科會一般型研究計畫 2002/8/1 ~ 2003/7/31
9.	利用真菌生產食品工業酵素BETA-D-GLUCOSIDASE最適化條件之探討，國科會一般型研究計畫 2000/8/1 ~ 2001/7/31
10.	以代謝抑制劑促進酵母菌細胞生物轉換產生天然單體香料乙酸苯乙酯之研究，國科會個別型計劃 1999/8/1 ~ 2000/7/31
11.	以酵母菌細胞生物轉換產生天然單體香料乙酸苯乙酯之研究，國科會個別型計劃 1998/8/1 ~ 1999/7/31
12.	天然單體香料乙酸苯乙酯合成酵素之純化及其性質之研究，國科會個別型計劃 1997/8/1 ~ 1998/7/31
13.	微生物香料乙酸苯乙酯之最適化生產條件之研究，國科會個別型計劃 1996/8/1 ~ 1997/7/31
14.	以酵母菌突變株產生天然單體香料乙酸苯乙酯之研究，國科會個別型計劃 1995/8/1 ~ 1997/2/28
15.	菎麻子油水解物中之脂肪酸成份對S.odorus產生 r-decalactone含量之影響，國科會個別型計劃 1992/8/1 ~ 1993/7/31

產學合作計畫(研9)

1.	提取萬壽菊生物活性成分方法之探討，2024/3/1 ~ 2024/9/30
2.	含中草藥乳液凝膠的性質檢測，2023/3/1 ~ 2023/9/30
3.	含中草藥高內相乳液的穩定性測試，2022/3/1 ~ 2022/8/31
4.	動物用中藥製劑之品質監測，2019/1/1 ~ 2019/12/31
5.	綠能智慧城市之自動化太陽能農場建置，2018/1/1 ~ 2018/12/31
6.	評估奈米鑽石嫁接美白成分之生物活性計畫，2017/8/1 ~ 2018/7/31
7.	重組蛋白的大量生產，2015/11/15 ~ 2017/11/14
8.	辨識牛樟椴木及牛樟芝的技術研發，2013/7/1 ~ 2013/10/31
9.	小金櫻抗過敏活性之研究，2012/10/1 ~ 2013/12/31
10.	牛樟芝篩選及抑癌功能評估，2012/6/1 ~ 2012/11/30
11.	小金櫻不同部位萃取物之美白功效，2011/9/1 ~ 2012/7/15
12.	以Pichia pastoris 大量表現alcohol acetyltransferase基因，2010/11/1 ~ 2010/12/31
13.	以Burkholderia sp.生產脂解酶之最佳條件，2010/9/1 ~ 2011/7/15
14.	開發含中草藥之功效性化妝保養品，2010/7/1 ~ 2010/12/31
15.	動物用藥劑型及穩定度之改良，2010/7/1 ~ 2010/12/31
16.	溶劑種類及區分對小飛揚草抗氧化性質之影響，2009/9/1 ~ 2010/7/15
17.	動物用中草藥保健產品之開發，2009/3/1 ~ 2009/8/31
18.	不含paraben防腐劑之新型產品開發暨微生物品質檢測平台之建立，2009/3/1 ~ 2009/8/31
19.	具轉酯活性脂解酶之純化及特性探討，2008/9/1 ~ 2009/7/15
20.	利用磁性奈米粒子固定脂解酶以生產生質柴油，2007/9/1 ~ 2008/7/15
21.	高轉酯活性脂解菌株之篩選及其最適培養基組成之探討，2006/9/1 ~ 2007/7/15
22.	以Pichia pastoris 大量表現alcohol acetyltransferase基因，2005/9/1 ~ 2006/7/15
23.	液態深層培養羊肚菌之最適化探討，2004/9/1 ~ 2005/7/15

期刊論文 (Journal Paper)

1.	Shiow-Ling Lee, Ming-Hong Xu, I-Ching Kuan, Chi-Yang Yu, Wei-Chen Kao, Fu-Yin Deng(2016). Immobilization of lipase from Candida rugosa and its application for the synthesis of biodiesel in a two-step process.. Asia-Pac. J. Chem. Eng.,, 11, 910-917. SCIE(SCI)
2.	Shiow-Ling Lee, Liang-Yu Huang, I-Ching Kuan, Chi-Yang Yu(2013). Optimized production of biodiesel from waste cooking oil by lipase immobilized on magnetic nanoparticles.. Int. J. Mol. Sci., 14, 24074-2408. SCIE(SCI)
3.	Lee, SL, Chen, WC, Liou, SS, Liu, IM(2013). Effect of topical application of chlorogenic acid on excision wound healing in rats.. Planta Med., 79, 616-621. SCIE(SCI)
4.	Shiow-Ling Lee, Chia-Chi Lee,, I-Ching Kuan, Chi-Yang Yu, Bing-Hong Tsai, Wei-Ting Lee(2013). Optimizing the production of biodiesel using lipase entrapped in biomimetic silica.. Energies., 6, 2052-2064. SCIE(SCI)
5.	I-Ching Kuan, Chia-Chi Lee, Bing-Hong Tsai, Shiow-Ling Lee, Wei-Ting Lee, Chi-Yang Yu(2013). Optimizing the Production of Biodiesel Using Lipase Entrapped. Energies, 6, 2052-2064. SCIE(SCI)
6.	S.-L. Lee, Lo, C.-F., I-Ching Kuan, Chi-Yang Yu(2012). Optimization of lipase production by Burkholderia sp. using response surface methodology.. Int. J. Mol. Sci., 13, 14889-1489. SCIE(SCI)
7.	Shiow-Ling Lee, Wei-Cheng Chen, Thing-Fong Tzeng, Shorong-Shii Liou, I-Min Liu(2012). Wound repair and anti-inflammatory potential of Lonicera japonica in excision wound-induced rats.. BMC Complementary and Alternative Medicine, 12, 226-235. SCIE(SCI)
8.	Shiow-Ling Lee, Chiao-An Chuang, I-Ching Kuan, Chi-Yang Yu(2012). Alkyl-substituted methoxysilanes enhance the activity and stability of d-amino acid oxidase encapsulated in biomimetic silica. Biotechnol Lett, 34, 1493–1498. SCIE(SCI)
9.	S.-L. Lee, K.-H. Tsui, I-Ching Kuan, T.-H. Feng, P.-L. Chang, Chung, L.-C., H.-H. Juang(2012). L-mimosine blocks cell proliferation via upregulation of B-cell translocation gene 2 and N-myc downstream regulated gene 1 in prostate carcinoma cells.. Am. J. Physiol. Cell. Physiol., 302, C676–C685.. SCIE(SCI)
10.	S.-L. Lee, Chung, L.-C., K.-H. Tsui, T.-H. Feng, P.-L. Chang, H.-H. Juang(2011). Curcumin provides potential protection against the activation of hypoxia and prolyl 4-hydroxylase inhibitors on prostate-specific antigen expression in human prostate carcinoma cells.. Mol. Nutr. Food Res., 55, 1666–1676. SCIE(SCI)
11.	S.-L. Lee, Lin, M.-H., C.-C. Chou.(2011). Acid adaptation affects the viability of Listeria monocytogenes BCRC 14846 and Salmonella Typhimurium BCRC 10747 exposed to disinfectants at 25℃ and 40℃.. Foodborne Pathog. Dis., 8, 1077-1081.. SCIE(SCI)
12.	Shiow-Ling Lee, Chen, Y.-F., C.-C. Chou.(2011). Fermentation with Aspergillus awamori enhanced contents of amino nitrogen and total phenolics as well as the low-density lipoprotein oxidation inhibitory activity of black soybeans.. J. Agric. Food Chem., 59, 3974–3979.. SCIE(SCI)
13.	Shiow-Ling Lee, Chen, G.-C., I-Ching Kuan, Chi-Yang Yu, J.-R. Hong, B.-H. Tsai(2011). 2011. Activity enhancement and stabilization of lipase from Pseudomonas cepacia in polyallylamine-mediated biomimetic silica.. Biotechnol. Lett., 33, 525–529. SCIE(SCI)
14.	Shiow-Ling Lee, Jian-Cheng Wu, I-Ching Kuan, Chi-Yang Yu, Chen-Wei Tsai, Chiao-An Chuang(2010). Stabilization of D-amino acid oxidase from Rhodosporidium toruloides by encapsulation in polyallylamine-mediated biomimetic silica. Biochem. Eng. J., 49, 408-413. SCIE(SCI)
15.	Shiow-Ling Lee, Hao-Chieh Hsieh, I-Ching Kuan, Chi-Yang Yu, Gee-Yeng Tien, Yi-Jen Wang(2009). Stabilization of D-amino acid oxidase from Rhodosporidium toruloides by immobilization onto magnetic nanoparticles. Biotechnol. Lett., 31(4), 557-263. SCIE(SCI)
16.	I-Ching Kuan, Jhen-Yang Chi, Chiyang Yu, Shiow-Ling Lee(2009). Biochemical characterization of his-tagged zebra fish D-amino acid oxidase expressed in E. coli. Journal of Bioscience and Bioengineering, 2009. SCIE(SCI)
17.	Kaun-Chun Chen, Shiow-Ling Lee, Guor-Tzo Wei, Hao-Chieh Hsieh, Chi-Yang Yu(2009). Immobilization of cellulase from Trichoderma reesei onto magnetic nanoparticles and effects of ionic liquid on cellulose hydrolysis. Immobilization of cellulase from Trichoderma reesei onto magnetic nanoparticles and effects of ionic, 2009. SCIE(SCI)
18.	Kai-Ho Mak, Chi-Yang Yu, I-Ching Kuan, Shiow-Ling Lee(2009). Some properties of immobilized Pseudomonas cepacia lipase onto magnetic nanoparticles. Journal of Bioscience and Bioengineering, 2009. SCIE(SCI)
19.	S.-L. Lee, H.-Y. Cheng, W.-C. Chen, C.-C. Chou.(2008). Production of gamma-decalactone from ricinoleic acid by immobilized cells of Sporidiobolus salmonicolor.. Process Biochem., 33(4), 453-459. SCIE(SCI)
20.	李綉鈴、黃國榮、余嚴尊（2003）。臺灣醱酵麴菌之研究(I)保存菌之酵素生成性.。食品科學，20(6)，567-573。SCIE(SCI)
21.	李綉鈴、周正俊、吳淳美（2003）。利用反應曲面法尋求 Sporobolomyces odorus 產生 gamma-decalactone 之最適條件.。中國農化學會誌.，31(1)，28-34。SCIE(SCI)
22.	李綉鈴（1992）。Sporobolomyces odorus 產生揮發性香味成份之影響因子。中國農化會誌.，30(4)，471-483。SCIE(SCI)
23.	李綉鈴（1991）。Kluveromyces lactis, Ceratocystis moniliformis 及 Sporobolomyces odorus 產生之香氣成份鑑定。中國農化會誌.，29(1)，43-53.。SCIE(SCI)

研討會論文 (Conference Paper)

1.	Tzu-Ting Yu, Chiung-Cheng Huang, Shiow-Ling Lee(2018). Preparation of thermosensitive nano-structured hydrogels of poly(N-isopropyl acrylamide) with chloro. 2018 BEST Conference & International Symposium on Biotechnology and Bioengineering. R.O.C.
2.	I-Ching Kuan, Chun-Ling Chen, Shiow-Ling Lee, Chi-Yang Yu(2017). Microbial biodiesel production by acid-catalyzed direct transesterification of Rhodotorula glutinis biomass. YABEC 2017（頁 109）. United States of America.
3.	I-Ching Kuan, Sing-Yu Chen, Shiow-Ling Lee, Chi-Yang Yu(2016). Enzymatic production of 4-methylthio-2-oxobutyric acid using Trigonopsis variabilis D-amino acid oxidase immobilized on polydopamine-coated magnetic nanoparticles. YABEC 2016（頁 141）. United States of America.
4.	I-Ching Kuan, Chia-Jung Chou, Shiow-Ling Lee, Chi-Yang Yu(2016). Protective effect of Mimosa pudica extracts on UVB-induced damage in human dermal fibroblasts. YABEC 2016（頁 53）. United States of America.
5.	Chia-Jung Chou, Chi-Yang Yu, I-Ching Kuan, Shiow-Ling Lee(2016). Protective effect of Mimosa pudica extracts on UVB-induced damage in human dermal fibroblasts,. YABEC 2016. United States of America.
6.	I-Ching Kuan, Li-Ming Huang, Chi-Yang Yu, Shiow-Ling Lee(2015). Biomimetic silicification of Rhodosporidium toruloides D-amino acid oxidase catalyzed by ubiquitin. Proceedings of YABEC 2015 symposium. United States of America.
7.	I-Ching Kuan, Fu-Yin Deng, Shiow-Ling Lee, Chi-Yang Yu, Ming-Hong Xu(2015). Immobilization of lipase from Candida rugosa and its application for the synthesis of biodiesel in a two-step process. Proceedings of the BEST conference & international symposium on biotechnology and bioengineering. United States of America.
8.	I-Ching Kuan, Shing-Yu Chen, Shiow-Ling Lee, Chi-Yang Yu(2015). Immobilization of D-amino acid oxidase via a biomimetic film and its application for the resolution of D/L-methionine. Proceedings of the BEST conference & international symposium on biotechnology and bioengineering. United States of America.
9.	I-Ching Kuan, Chia-Fang Tsai, Shiow-Ling Lee, Chi-Yang Yu(2015). Anti-oxidative activity and proliferation effect of Mimosa pudica on human dermal fibroblasts. Proceedings of the BEST conference & international symposium on biotechnology and bioengineering. United States of America.
10.	I-Ching Kuan, Yu-An Huang, Shiow-Ling Lee, Chi-Yang Yu(2014). Enhancement of 2-phenylthanol production by Pichia fermentans L-5 with in situ product recovery technique. YABEC 2014（頁 83）. United States of America.
11.	I-Ching Kuan, Ming-Hong Xu, Shiow-Ling Lee, Chi-Yang Yu, Fu-Yin Deng(2014). Toward an efficient conversion of waste cooking oil to biodiesel:characteriztion of Candida rugosa lipase immobilized on diaion HP-20. YABEC 2014（頁 189）. United States of America.
12.	I-Ching Kuan, Tzu-Ting Liao, Shiow-Ling Lee, Chi-Yang Yu(2013). Stabilization of Rhodosporidium toruloides D-amino acid oxidase via biosilicification catalyzed by the chimeric protein of ubiquitin and R5 silaffin. WCCE9&APCChE 2013（頁 74）. United States of America.
13.	I-Ching Kuan, Liang-Yu Huang, Shiow-Ling Lee, Chi-Yang Yu(2013). Optimized production of biodiesel from waste cooking oil by lipase immobilized on magnetic nanoparticles. 2013 Joint of Japan/ Taiwan/ Korean Chemical Engineering Conference & Kyushu Seminar（頁 109-111）. United States of America.
14.	I-Ching Kuan, Cheng-Bin Zheng, Shiow-Ling Lee, Chi-Yang Yu(2013). Enzymatic properties of an E. coli-expressing Burkholderia lipase. YABEC 2013（頁 99）. United States of America.
15.	I-Ching Kuan, Shin-Fu Wang, Shiow-Ling Lee, Chi-Yang Yu(2013). Immobilization of Rhodosporidium toruloides D-amino acid oxidase via silaffin-mediated biomimetic silicification. The 18th symposium of young asian biochemical engineers community（頁 59）. United States of America.