姓名 許垤棋 老師 (Sheu, Dey-Chyi)
職級 教授  
單位 生物工程學系  
職務  
電話 02-21822928 轉 6326  
手機 0936676680  
email dcsheu@ttu.edu.tw  
網址  

  • 德國 Duesseldorf和Erlangen-Nuernburg Microbiology 肄業 (1985/10 至 1987/3)
  • 海洋大學 食品科學 碩士 (1977/9 至 1979/6)
  • 海洋大學 食品科學 學士 (1973/9 至 1977/6)
  • 大同大學 生物工程系 教授 (2003/2 至 今)
  • 大同大學 生物工程系 副教授 (1995/2 至 2003/1)
  • 大同大學 生物工程系 講師 (1987/6 至 1995/1)
  • 大同大學 應用生物籌備處 助理研究員 (1983/3 至 1985/8)
  • 中國新藥公司 新莊醱酵工廠 研究人員 (1982/2 至 1983/2)
  • 食品科學  Food Science
  • 酵素學  Enzymology
  • 微生物學  Microbiology
  • 生化工程  Biochemical Engineering
  • 普通化學 General Chemistry
  • 應用微生物 Applied Microbiology
  • 食品科學概論 Introductory Food Science
  • 廢水微生物 Wasterwater Microbiology
專 利
  • 段國仁(職員)、許垤棋(職員)、畢家麟(學生), "一種利用複合細胞系統製造高純度果寡糖之方法," 中華民國專利，發明第170385號
  • 段國仁(職員)、許垤棋(職員), "果寡糖甜味料之製造方法," 中華民國專利，發明第076598號
  • 許垤棋(職員)、段國仁(職員)、吳靜怡(學生)、余玫靜(職員), "生產 L 型乳酸之方法," 中華民國專利，發明第 I 297360號, Jun 2008
期刊論文 Refereed Paper
  1. J. S. Wu, J. Y. Chang, C. Will Chen, M. T. Lin, D. C. Sheu and S. M. Lee, "Neokestose suppresses the growth of human melanoma A2058 cells via inhibition of the nuclear factor‑κB signaling pathway," Molecular Medicine Reports, Vol. 16, pp. 295-300, June. 2017
  2. S.F. Chow, D.C. Sheu and C.P. Liu, "Carbapenem-resistant Acinetobacter baumannii complex bacteraemia in elderly patients in northern Taiwan," Research Journal of Biotechnology, Vol. 10, No. 9, pp. 18-24, September 2015
  3. S.F. Chow, D.C. Sheu and C.P. Liu, "Biochemical and haematological parameters and the impact of hypoalbuminaemia on mortality in carbapenem-resistant Acinetobacter baumannii complex bacteraemia," Research Journal of Biotechnology, Vol. 10, No. 8, pp. 11-18, Aug. 2015
  4. C.F. Ken, W.W. Tsai, Lisa Wen, D.C. Sheu and C.T. Lin, "Properties of a 2,3-butanediol dehydrogenase from Taiwanofungus camphorata," Journal of the Chinese Chemical Society, Vol. 62, No.5, pp. 443-448, May 2015
  5. S. M. Lee, J. Y. Chang, J. S. Wu and D. C. Sheu, "Antineoplastic effect of a novel chemopreventive agent, neokestose, on the Caco-2 cell line via inhibition of expression of nuclear factor-κB and cyclooxygenase-2," Molecular Medicine Reports, 12(1): 1114-1118, Apr. 2015
  6. S. C. Chen, D. C. Sheu and K. J. Duan, "Production of fructooligosaccharides using beta-fructofuranosidase immobilized onto chitosan-coated magnetic nanoparticles," Journal of the Taiwan Institute of Chemical Engineers, Vol. 45, No. 4, pp. 1105–1110, July. 2014
  7. C. Y. Wang*, C. T. Lin, D. C. Sheu and C. Y. Liu, "L-Lactic acid fermentation by culture of Rhizopus oryzae using ammonia as neutralizing agent," Journal of the Taiwan Institute of Chemical Engineers, Vol. 45, pp. 1-5, Jan 2014
  8. C. Y. Huang, Y. T. Chen, L. Wen, D. C. Sheu and C. T. Lin, "A peroxiredoxin cDNA from Taiwanofungus camphorata: role of Cys31 in dimerization.," Molecular Biology Report, Vol. 41, No. 1, pp. 155-164, Jan. 2014
  9. D. C. Sheu*, J. Y. Chang, C. Y. Wang, C. T. Wu and C. J. Huang, "Continuous production of high-purity fructooligosaccharides and ethanol by immobilized Aspergillus japonicus and Pichia heimii," Bioprocess and Biosystems Engineering, Vol. 36, pp.1745-1751,Oct. 2013
  10. D. C. Sheu*, J. Y. Chang, Y. J. Chen and C. W. Lee, "Production of high-purity neofructooligosaccharides by culture of Xanthophyllomyces dendrorhous," Bioresource Technology, Vol. 132, pp. 432-435, March, 2013
  11. 周尚芳、許垤棋, "大台北地區過敏原特異型IgE 抗體之陽性比率與嚴重程度," 生物醫學暨檢驗雜誌, Vol. 24, No. 3, pp. 85-91, Sep. 2012
  12. Chung-Yih Wang, Yi-Chen Chen, Dey-Chyi Sheu and Tse Chuan Chou, "Molecularly imprinted polymers for the recognition of sodium dodecyl sulfate," Journal of the Taiwan Institute of Chemical Engineers, Vol. 43, No. 2, pp. 188–194, March. 2012
  13. Ya-Han Dai, Chich-Yu Huang, Lisa Wen, Dey-Chyi Sheu and Chi-Tsai Lin, "Lemon ascorbate peroxidase: cDNA cloning and biochemical characterization," Botanical Studies, Vol. 53, pp. 9-17 2012年3月
  14. Chung-Yih Wang, Hui-Fan Liao and Dey-Chyi sheu, "Enhancement of recombinant human macrophage colony-stimulating factor-production using culture systems with porous polymeric microspheres," J Taiwan Inst Chem Eng, Vol. 41, pp. 203-208, March. 2010
  15. C. Y. Huang, L. Wen, R. H. Juang, D. C. Sheu and C. T. Lin, "Monodehydroascorbate reductase cDNA from sweet potato: expression and kinetic studies," Botanical Studies, Vol. 51, pp. 37-44, Jan. 2010
  16. C. L. Kao, H. T. Lin, Y. W. Chen, Y. C. Chen, F. T. Tsai, Y. L. Chang, S. H. Chiou and D. C. Sheu, "Fibronectin suppresses lipopolysaccharide-induced liver damage and promotes the cytoprotection abilities of hepatocyte-like cells derived from human," Transplantation Proceedings, Vol. 39, No.10, pp. 3444-3445, Dec. 2007
  17. M. C. Yu, R. C. Wang, C. Y. Wang, K. J. Duan and D. C. Sheu*, "Enhanced production of L(+)-lactic acid by floc-form culture of Rhizopus oryzae," Journal of the Chinese Instute of Chemical Engineers, Vol. 38, pp. 223-228, 2007
  18. H-T Lin, C-L Kao, K-H Lee, Y-L Chang, S-H Chiou, F-T Tsai, T-H Tsai, D-C Sheu, L-LT Ho, H-H Ku, "Enhancement of insulin-producing cell differentiation from embryonic stem cells using pax4-nucleofection method," World Journal of Gastroenterology, Vol. 13, No. 11, pp. 1672-1679, March 2007
  19. C. C. Cheng, M. C. Yu, T. C. Cheng, D. C. Sheu*, K. J. Duan & W. L. Tai, "Production of high-content galacto-oligosaccharide by enzyme catalysis and fermentation with Kluyveromyces marxianus," Biotechnology Letters, Vol. 28, pp. 793-797, June 2006
  20. K. S. Chen, Y. A. Ku*, H. R. Lin, T. R. Yan, D. C. Sheu, T. M. Chen, "Surface grafting polymerization of N-vinyl-2-pyrrolidone onto a poly(ethylene terephthalate) nonwoven by plasma pretreatment and its antibacterial act," Journal of Applied Polymer Science, Vol.100, No. 1, pp. 803-809, April 2006
  21. T. C. Cheng, K. J. Duan*, D. C. Sheu, "Application of tris(hydroxymethyl) phosphine as a coupling agent for β-galactosidase immobilized on chitosan to produce galactooligosaccharides," Journal of Chemical Technology and Biotechnology, Vol. 81, No. 2, pp. 233-236, Feb. 2006
  22. K. S. Chen, Y. A. Ku*, H. R. Lin, T. R. Yan, D. C. Sheu, T. M. Chen and F. H. Lin, "Preparation and characterization of pH sensitive poly(N-vinyl-2-pyrrolidone/itaconic acid) copolymer hydrogels," Materials Chemistry and Physics, Vol. 91, pp. 484-489, June 2005
  23. T. C. Cheng, K. J. Duan* and D. C. Sheu, "Immobilization of β-fructofuranosidase from Aspergillus japonicus on chitosan using tris(hydroxymethyl)phosphine or glutaraldehyde as a coupling agent," Biotechnology Letters, Vol.27, pp. 335-338, March 2005
  24. S. L. Her, K. J. Duan*, D. C. Sheu, and C. T. Lin, "A repeated batch process of cultivation of Bifidobacterium longum," Journal of Industrial Microbiology and Biotechnology, Vol.31, pp, 427-432, Sep. 2004
  25. D. C. Sheu*, K. J. Duan, S. R. Jou, Y. C. Chen, and C. W. Chen, "Production of xylitol from Candida tropicalis by using an oxidation-reduction potential-stat controlled fermentation," Biotechnology Letters, Vol.25, pp. 2065-2069, Dec. 2003
  26. D. C. Sheu*, K. J. Duan, C. Y. Cheng, J. L. Bi, and J. Y. Chen, "Continuous production of high-content fructooligosaccharides by a complex cell system," Biotechnology Progress, Vol.18, pp.1282-1286, Dec. 2002
  27. D. C. Sheu, P. J. Lio, S. T. Chen, C. T. Lin and K. J. Duan*, "Production of fructooligosaccharides in high yield using a mixed enzyme system of β-fructofuranosidase and glucose oxidase," Biotechnology Letters, Vol.23, pp.1499-1503, Sep. 2001
  28. K. J. Duan, M. T. Lin, Y. C. Hung, C. T. Lin, C. Will Chen and D. C. Sheu, "Production of GST-SOD fusion protein by recombinant E coli XL1 Blue," J. Chem. Technol. Biotechnol, Vol.75, pp.722-728, May 2000
  29. 江國瑛、段國仁、許垤棊, "利用深層醱酵法生產靈芝多醣的研究," TATUNG Journal, Vol. 28, pp. 353-358, 1998
  30. D. C. Sheu, S. Y. Li, K. J. Duan and C. Will Chen, "Production of galactooligosaccharides by b-galactosidase immobilized on glutaraldehyde-treated chitosan beads.," Biotechnology Techniques, Vol. 12, pp. 273-276, 1998
  31. D. C. Sheu, C. I. Huang, and K. J. Duan, "Production of isomaltooligosaccharides by α-glucosidase immobilized in chitosan beads and by PEI-glutaraldehyde treated mycelia of Asp. carbonarious," Biotechnology Techniques, Vol. 11, pp. 287-291, 1997
  32. C. J. Chiang, W. C. Lee, D. C. Sheu and K. J. Duan, "Immobilization of b-fructofuranosidases from Aspergillus on methacrylamide-based polymeric beads for production of fructooligosaccharides," Biotechnology Progress, Vol. 13, pp. 577-582, 1997
  33. C.Y. Cheng, K. J. Duan, D.C. Sheu, and C. T. Lin, "Production of Fructooligosaccharides by Immobilized Mycelium of Asp. japonicus," J. Chem. Technol. Biotechnol., Vol. 66, pp. 135-138, 1996
  34. K. J. Duan, D. C. Sheu and C. T. Lin, "Transglucosylation of a fungal α-Glucosidase: The Enzyme Properties and Correlation of Isomaltooligosaccharide Production," Annals of The New York Academy of Scienses, Vol. 750, pp. 325-328
  35. K. J. Duan, D. C. Sheu, S. C. Hsueh, and M. T. Lin, "Reaction Mechanism of Isomaltooligosaccharides Synthesis by α-glucosidase from Aspergillus carbonarious.," Biotechnology Letters, Vol. 16, pp. 1151-1156, 1994
  36. C. T. Lin, M. T. Lin, D. C. Sheu, and K. J. Duan, "Cloning and Characterization of a Copper/Zinc Superoxide Dismutase Gene from Aspergillus japonicus," Taiwania, Vol. 39, pp. 73-79, 1994
  37. K. J. Duan, J. S. Chen, and D. C. Sheu, "Kinetic studies and mathematical model for enzymatic production of fructooligosaccharides from sucrose," Enzyme Microbial Technology, Vol. 16, pp. 334-339, 1994
  38. 許垤棊、王錫賢、黃詩芳、汪曉芬、段國仁, "利用Aspergillus niger ATCC 424185之胞內 alpha-D-葡萄糖苷酶生產異麥芽寡糖之研究," 中國農業化學會誌, Vol. 31, pp. 740-751, 1993
  39. K. J. Duan, D. C. Sheu, J. S. Chen, "Purification and characterization of β- fructofuranosidase from Asp. japonicus TIT-KJ1," Biosci. Biotech. Biochem., Vol. 57, pp. 1811-1815, 1993
  40. 段國仁、許垤棊, "利用Bacillus circulans以鹼性培養基生產環狀糊精葡萄糖苷轉移酶及其特性研究," 中國農業化學會誌, Vol. 30, pp. 273-281, 1992
  41. Nomoto M, Chen CC, Sheu DC, "Purification and characterization of cyclodextrin glucanotransferase from an alkalophilic bacterium of Taiwan," Agricultural and Biological Chemistry, Vol. 50, pp. 2701-2707, 1986
  42. D. C. Sheu and C. Chen, "The activity Test and Fermentation Study of Pullulanase," Tatung Journal, Vol.16, pp.325-328
國際研討會論文 International Conference Paper
  1. Guan-Hua Chu, Chih-Chuan Tseng and Dey-Chyi Sheu, "Optimization of Fermentation Conditions for Lincomycin Production by Submerged Culture of Streptomyces lincolnensis," 2018 BEST Conference & International Symposium on Biotechnology and Bioengineering, P-II-62
  2. Y.T. Jhou and D.C. Sheu*, "Production of xanthan gum from glycerol by culture of Xanthomonas sp. YT-24," Proceeding of The 2016 BEST Conference & International Symposium on Biotechnology and Bioengineering, P-1 (PA-5)
  3. S.M. Lee*, J.Y. Chang and D.C. Sheu, "Preparation of yeast cell wall 6G-fructofuranosidase," Proceeding of The 2016 BEST Conference & International Symposium on Biotechnology and Bioengineering, P-11 (PD-2)
  4. C. J. Huang, S. M. Lee, H. L. Peng and D. C. Sheu, "Production of high-purity neofructooligosaccharides by two-step fermentation with Xanthophyllomyces dendrorhous and Baker's yeast," Proceedings of the 2015 Conference & International Symposium on Biotechnology and Bioengineering, P1-T1-9, National Taiwan University of Science and Technology, Taipei, Taiwan, -
  5. Dey-Chyi Sheu, Jan-Yi Chang, Yan-Jen Chen and Cheng-Wei Lee, "Production of neofructooligosaccharides by cultures of Xanthophyllomyces dendrorhous," 5th International Conference on Industrial Bioprocesses (IFIB 2012), IFIB-2012, p. 304, October 7-10. 2012, Taipei, Taiwan
  6. Dey-Chyi Sheu, Chang-Ta Wu and Chung-Yih Wang, "Production of high-content fructooligosaccharides by immobilized Aspergillus japonicus and Pichia heimii," 13th Asia Pacific Confederation of Chemical Engineering Congress, pp. 65, Oct. 5-8, 2010, Taipei
  7. D. C. Sheu, C. Y. Wang, P. H. Huang and K. J. Duan, "Fructosyltransferase production by Aspergillus japonicus in submerged and solid-state fermentation," 2008 Taiwan/Korea/Japan ChE Conference, pp. 88, Nov. 20-22, 2008
  8. D. C. Sheu*, C. Y. Wang, C. W. Chi, and T. Wang, "Effect of urea concentration on production of L-lactic acid and chitosan by culture of Rhizopus oryzae," Taiwan Chitin and Chitosan Symposium, Chung-Li, pp. 442-445, May 2007
  9. D. C. Sheu*, K. J. Duan, C. Y. Wang, I. C. Lin, C. Y. Wu, "Enhanced production of L(+)-lactic acid by floc-form culture of Rhizopus oryzae," 12-th Symposium of Young Asian Biochemical Engineers' Community, PA-04, p.54, Nov. 2006
區域研討會論文 Domestic Conference Paper
  1. Yu-Chih Lin and Dey-Chyi Sheu, "Neofructooligosaccharides production through the catalytic action of 6G-fructofuranosidase from culture of Xanthophyllomyces dendrorhous," 2014生物技術暨生物工程研討會(東海大學), P2-1
  2. Ching-Ya Fang and Dey-Chyi Sheu, "Purification of 6G-fructofuranosidase from culture of Xanthophyllomyces dendrorhous," 2014生物技術暨生物工程研討會(東海大學), P2-2
  3. 陳育星、許垤棋, "兩株鏈黴菌的轉麩胺醯酶的生化特性比較," 2013生物技術暨生物工程研討會(虎尾科技大學), P1-22
  4. 李政衛、許垤棋, "比較兩株法夫酵母胞外葡萄糖苷轉移酶的生化特性," 2013生物技術暨生物工程研討會(虎尾科技大學), P1-23
  5. 許垤棋、張建裕, "新果寡糖的分析和純化," 2013生物技術暨生物工程研討會(虎尾科技大學), P1-63
  6. 游竣凱、許垤棋, "利用葡萄糖苷轉移酶與Pichia heimii共固定化顆粒生產高純度異麥芽寡糖," 第17屆生化工程研討會, p. 284, June 2012
  7. 詹渝斐、許垤棋, "利用乳糖誘導基因重組大腸桿菌生產beta-葡萄糖苷酶之研究," 第17屆生化工程研討會, p. 283, June 2012
  8. 翁茂盛、朱砡賢、許垤棋, "果糖轉移酶催化反應機制的研究," 第16屆生化工程研討會, 大同大學，p. 186
  9. 吳政達、王鐘毅、許垤棋, "利用二種固定化細胞生產高純度果寡糖," 第16屆生化工程研討會, 大同大學，p. 185
  10. 楊久盈、陳志成、許垤棋, "以乳糖誘導基因重組大腸桿菌生產β-glucosidase之醱酵策略探討," 第16屆生化工程研討會, 大同大學，p. 184
  11. 許垤棋、王榮基、翁茂盛、吳政達、甘魯生, "綠能/綠色化學月刊," 2010中國化學會年會, Poster ED001，p. 176
  12. 曾柏瑞、許垤棋, "比較四株黴菌在醱酵槽中的果糖轉移脢產量," 第15屆生化工程研討會, pp. 242, June, 2010
  13. 許垤、劉芝妤、陳筱祺, "利用根黴菌醱酵生產L型乳酸銨," 第14屆生化工程研討會, 中興大學, p. 214, June 2009
  14. D. C. Sheu, C. Y. Wang and L. M. Li, "Ammonium L-lactate fermentation by culture of Rhizopus arrhizus," 第13屆生化工程研討會, Jun. 2008
  15. 許垤綦;、段國仁、賴宜涵、溫晼媜、吳靜怡, "控制米根黴的形態以提高 L 型乳酸的產量," 第11屆生化工程研討會, P7-025, June 2006
  16. 許垤棊*、鄭昭君、戴偉倫, "用混合酵素系統生產高純度半乳寡糖," 第52屆化學工程年會(聯合大學), PB-11, Nov. 2005
  17. C. C. Kuo, M. C. Yu, D. C. Sheu*, R. C. Wang, K. J. Duan, "Photocatalytic pretreatment of plasma display panel wastewater for biodegradation enhancement," 第52屆化學工程年會(聯合大學), PB-28, Nov. 2005
  18. D. C. Sheu*, C. C. Ho, "Fermentation of high-content fructo-oligosaccharides by bifidobacteria," 乳酸菌前瞻科技及其應用(大同大學), 第67頁, Sep. 2005。
  19. C. C. Kou, M. C. Yu, D. C. Sheu* and K. J Duan, "Influence of different nitrogen source on mycelial morphology of Rhizopus oryzae and L(+)-lactic acid production," 第十屆生化工程研討會(台灣大學), 第42頁, June. 2005。
  20. 許垤棊, "高純度寡糖對比菲徳氏菌增殖的影響," 中國化學工程年會(南台科技大學), 第63頁, Nov. 2004。
  21. Sheu, D. C.*, K. J. Duan, and C. W. Chi, "Photocatalytic disinfection of TiO2-containing coating under fluorescent light," Workshop on Visible Light Photocatalysts (東華大學), pp. 42, July, 2004
  22. 許垤棊、段國仁、紀智偉、陳明宗、黃雅淑, "奈米二氧化太塗料的抗菌作用," 第九屆生化工程研討會暨農業生物產業研討會 (大葉大學), pp. 30, June, 2004
  23. 許垤棊、段國仁、何金柱、徐雅亭, "高純度半乳寡糖對比非徳氏菌增殖的影響," 第九屆生化工程研討會暨農業生物產業研討會 (大葉大學), pp. 36, June, 2004
  24. 鄭昭君、許垤棊、段國仁, "高純度半乳寡糖的生產," 第九屆生化工程研討會暨農業生物產業研討會 (大葉大學), pp. 115, June, 2004
  25. Ho, C. C., D. C. Sheu, and K. J. Duan, "Improving two-cell system for the production of high-content fructooligosaccharides by substituting air with oxygen," 第八屆生化工程研討會 (義守大學), pp. 29, June, 2003
  26. Shu, Y. T., D. C. Sheu, and K. J. Duan, "Depletion of digestible sugars in commercial galactooligosaccharides by Kluyveromyces marxianus," 第八屆生化工程研討會 (義守大學), pp. 39, June, 2003
  27. Lin, I. C., D. C. Sheu, and K. J. Duan, "Production of L (+)-lactic acid by Rhizopus oryzae," 第八屆生化工程研討會 (義守大學), pp. 59, 2003
技術報告 Technical Report
  1. 鄭慈千、段國仁、許垤棊, "酵素生產果寡糖與半乳寡糖," 化工, 53卷，第6期，第151-161頁。
  2. 許力中、許垤棊*、段國仁, "木糖醇的生產 - 酵母醱酵法," 化工技術, 第95期，第190-199頁。